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ChemicalBook > Product Catalogue >API >Digestive system drugs >Antacid and Mucosal protective Drugs >R-(+)-Lansoprazole

R-(+)-Lansoprazole

R-(+)-Lansoprazole Structure
  • ₹9201.25
  • Product name: R-(+)-Lansoprazole
  • CAS: 138530-94-6
  • MF: C16H14F3N3O2S
  • MW: 369.36
  • EINECS:1308068-626-2
  • MDL Number:MFCD13196699
  • Synonyms:(R)-2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole;1H-Benzimidazole, 2-[(R)-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]- (9CI);1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-, (R)-;R-(+)-Lansoprazole;2-[(R)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole;T 168390;TAK 390;2-[[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzoimidazole
Price1 Properties Safety Information Description
1 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML2624
  • Product descriptionDexlansoprazole ≥98% (HPLC)
  • Packaging50MG
  • Price₹9201.25
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML2624 Dexlansoprazole ≥98% (HPLC) 50MG ₹9201.25 2022-06-14 Buy

Properties

Melting point :66-68?C
Boiling point :555.8±60.0 °C(Predicted)
Density :1.50±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :9.56±0.10(Predicted)
color :Off-White to Dark Brown
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

Lansoprazole is a proton pump inhibitor that irreversibly inactivates the H+/K+-stimulated ATPase pumps in parietal cells, inhibiting gastric acid secretion and increasing intragastric pH. It is a 1:1 racemic mixture of (R)-lansoprazole and (S)-lansoprazole, both of which are pharmacologically active. (R)-Lansoprazole is an enantiomerically pure form of lansoprazole. It can inhibit acid formation in isolated canine parietal cells with an IC50 value of 59 nM and inhibit the H+/K+-ATPase with an IC50 value of 4.2 μM.

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Suppliers and manufacturers

TAGOOR LABORATORIES PVT LTD RP Industries GLP Pharma Standards Metrochem API Private Limited Sekhment pharmaventures Apotex Pharmachem India Pvt Ltd Piramal Pharma Solutions Lupin Ltd Chemeca Drugs Private Limited (Vegesna Laboratories Pvt Ltd) Enal Drugs Pvt Ltd