Exemestane
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- ₹11961.63 - ₹55218.33
- Product name: Exemestane
- CAS: 107868-30-4
- MF: C20H24O2
- MW: 296.4
- EINECS:643-090-2
- MDL Number:MFCD00866994
- Synonyms:ExeMestane (USP);1,4-Androstadien-3,17-dione-6-Methylene-d2;(8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dione;ExeMestine;(8R,9S,10R,13S,14S)-10,13-diMethyl-6-Methylene-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione;ExeMestane SynonyMs 6-Methylenandrosta-1,4-diene-3,17-dione;PNU155971;Exemestane for system suitability
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- 1G
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1634
- Product descriptionExemestane Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹11961.63
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPZ0006
- Product descriptionExemestane ≥98% (HPLC)
- Packaging5MG
- Price₹14115.8
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPZ0006
- Product descriptionExemestane ≥98% (HPLC)
- Packaging25MG
- Price₹55218.33
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | PHR1634 | Exemestane Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹11961.63 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PZ0006 | Exemestane ≥98% (HPLC) | 5MG | ₹14115.8 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PZ0006 | Exemestane ≥98% (HPLC) | 25MG | ₹55218.33 | 2022-06-14 | Buy |
Properties
Melting point :155.13°C
Boiling point :453.7±45.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
form :powder
color :white to off-white
optical activity :[α]/D +250 to +300°, c = 1 in methanol
InChI :InChI=1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
InChIKey :BFYIZQONLCFLEV-DAELLWKTSA-N
SMILES :C1(=O)C=C2[C@](C)(C=C1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)C(=O)CC3)CC2=C
CAS DataBase Reference :107868-30-4(CAS DataBase Reference)
Boiling point :453.7±45.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
form :powder
color :white to off-white
optical activity :[α]/D +250 to +300°, c = 1 in methanol
InChI :InChI=1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
InChIKey :BFYIZQONLCFLEV-DAELLWKTSA-N
SMILES :C1(=O)C=C2[C@](C)(C=C1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)C(=O)CC3)CC2=C
CAS DataBase Reference :107868-30-4(CAS DataBase Reference)
Safety Information
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Description
Exemestane is a third generation, irreversible steroidal aromatase inhibitor (Ki = 10.2 nM; Kinact = 26 nM) that induces aromatase degradation leading to a decrease in estrogen levels in plasma. As an androgen analog, exemestane exhibits androgenic effects and has been shown to decrease total and HDL cholesterol, apo A1, and total triglyceride levels. Marketed under the trade name Aromasin?, exemestane has been used to treat estrogen receptor-positive breast cancers in post-menopausal women.More related product prices
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