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ChemicalBook > Product Catalogue >API >Antipyretic analgesics >Antigout Drugs >Etoricoxib

Etoricoxib

Etoricoxib Structure
  • ₹7308 - ₹9785.8
  • Product name: Etoricoxib
  • CAS: 202409-33-4
  • MF: C18H15ClN2O2S
  • MW: 358.84
  • EINECS:682-421-5
  • MDL Number:MFCD06797512
  • Synonyms:Etoricoxib Solution, 100ppm;Etoricoxib(5-chloro-6'-Methyl-3-(4-(Methylsulfonyl)phenyl)-2,3'-bipyridine;Etoricoxib (200 mg);Etoricoxib impurity A;Etoricoxib, >=98%;5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine;ETORICOXIB;5-Chloro-6'-methyl-3-[4-(methylsulfonyl) phenyl]-2,3'-bipyridine
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product number32097
  • Product descriptionEtoricoxib VETRANAL?, analytical standard
  • Packaging25MG
  • Price₹9785.8
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number E 0687
  • Product descriptionEtoricoxib, ≥98%
  • Packaging25mg
  • Price₹7308
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 32097 Etoricoxib VETRANAL?, analytical standard 25MG ₹9785.8 2022-06-14 Buy
ottokemi E 0687 Etoricoxib, ≥98% 25mg ₹7308 2022-05-26 Buy

Properties

Melting point :134-135°C
Boiling point :510.0±50.0 °C(Predicted)
Density :1.298±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO : 100 mg/mL (278.68 mM; Need ultrasonic)
pka :4.5(at 25℃)
form :Solid
color :Light yellow to yellow
BRN :8073797
InChIKey :MNJVRJDLRVPLFE-UHFFFAOYSA-N
CAS DataBase Reference :202409-33-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H310 Fatal in contact with skin Acute toxicity,dermal Category 1, 2 Danger GHS hazard pictograms P262, P264, P270, P280, P302+P350,P310, P322, P361, P363, P405, P501
Precautionary statements:
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

Etoricoxib is a dipyridinyl compound that demonstrates high in vitro and ex vivo selectivity for COX-2 over COX-1 in several assays, e.g., in the production of PGE2 by CHO cells expressing either COX-2 (IC50 = 79 nM) or COX-1 (IC50 > 50 μM). Oral etoricoxib is well absorbed and metabolized extensively via oxidation, with metabolites excreted largely in the urine.

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