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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antiviral drugs >Zidovudine

Zidovudine

Zidovudine Structure
  • ₹3400 - ₹142467.83
  • Product name: Zidovudine
  • CAS: 30516-87-1
  • MF: C10H13N5O5
  • MW: 283.24
  • EINECS:623-849-4
  • MDL Number:MFCD00006536
  • Synonyms:3'-Deoxy-3'-azidothymi;1-[4-azido-5-(hydroxymethyl)-2-tetrahydrofuranyl]-5-methylpyrimidine-2,4-dione;1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione;1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione;1-[4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione;1-[4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione;3'-Azido-3'-deoxythymidine, >=99%;Zidovudine solution
12 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL

Package

  • 25MG
  • 100MG
  • 250MG
  • 500mg
  • 1G
  • 1ML
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberA2052
  • Product description3'-Azido-3'-deoxythymidine
  • Packaging1G
  • Price₹3400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA2052
  • Product description3'-Azido-3'-deoxythymidine
  • Packaging5G
  • Price₹8900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberZ-011
  • Product descriptionZidovudine solution 1.0?mg/mL in methanol, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹6420
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA2169
  • Product description3′-Azido-3′-deoxythymidine ≥98% (HPLC)
  • Packaging25MG
  • Price₹8237.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1292
  • Product descriptionZidovudine Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹9818.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA2169
  • Product description3′-Azido-3′-deoxythymidine ≥98% (HPLC)
  • Packaging100MG
  • Price₹22580.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA2169
  • Product description3′-Azido-3′-deoxythymidine ≥98% (HPLC)
  • Packaging250MG
  • Price₹49513.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA2169
  • Product description3′-Azido-3′-deoxythymidine ≥98% (HPLC)
  • Packaging1G
  • Price₹142467.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number61898
  • Product description3-Azido-3-Deoxythymidine extrapure, 99%
  • Packaging25mg
  • Price₹4160
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number61898
  • Product description3-Azido-3-Deoxythymidine extrapure, 99%
  • Packaging100mg
  • Price₹10680
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number61898
  • Product description3-Azido-3-Deoxythymidine extrapure, 99%
  • Packaging250mg
  • Price₹20160
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number61898
  • Product description3-Azido-3-Deoxythymidine extrapure, 99%
  • Packaging500mg
  • Price₹34390
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A2052 3'-Azido-3'-deoxythymidine 1G ₹3400 2022-05-26 Buy
TCI Chemicals (India) A2052 3'-Azido-3'-deoxythymidine 5G ₹8900 2022-05-26 Buy
Sigma-Aldrich(India) Z-011 Zidovudine solution 1.0?mg/mL in methanol, certified reference material, Cerilliant? 1ML ₹6420 2022-06-14 Buy
Sigma-Aldrich(India) A2169 3′-Azido-3′-deoxythymidine ≥98% (HPLC) 25MG ₹8237.83 2022-06-14 Buy
Sigma-Aldrich(India) PHR1292 Zidovudine Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹9818.28 2022-06-14 Buy
Sigma-Aldrich(India) A2169 3′-Azido-3′-deoxythymidine ≥98% (HPLC) 100MG ₹22580.95 2022-06-14 Buy
Sigma-Aldrich(India) A2169 3′-Azido-3′-deoxythymidine ≥98% (HPLC) 250MG ₹49513.55 2022-06-14 Buy
Sigma-Aldrich(India) A2169 3′-Azido-3′-deoxythymidine ≥98% (HPLC) 1G ₹142467.83 2022-06-14 Buy
SRL 61898 3-Azido-3-Deoxythymidine extrapure, 99% 25mg ₹4160 2022-05-26 Buy
SRL 61898 3-Azido-3-Deoxythymidine extrapure, 99% 100mg ₹10680 2022-05-26 Buy
SRL 61898 3-Azido-3-Deoxythymidine extrapure, 99% 250mg ₹20160 2022-05-26 Buy
SRL 61898 3-Azido-3-Deoxythymidine extrapure, 99% 500mg ₹34390 2022-05-26 Buy

Properties

Melting point :113-115 °C (lit.)
alpha :D25 +99° (c = 0.5 in water)
Boiling point :410.43°C (rough estimate)
Density :1.3382 (rough estimate)
refractive index :47 ° (C=1, H2O)
Flash point :9℃
storage temp. :2-8°C
solubility :H2O: 50 mg/mL
pka :pKa 9.53(H2O t = 25.0±0.1 I = 0.00) (Uncertain)
form :Powder
color :White to Off-white
Water Solubility :1-5 g/100 mL at 17 ºC
Sensitive :Light Sensitive & Hygroscopic
Merck :14,10123
BRN :3595791
BCS Class :1,3
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :HBOMLICNUCNMMY-BWZBUEFSSA-N
CAS DataBase Reference :30516-87-1(CAS DataBase Reference)
IARC :2B (Vol. 76) 2000
EPA Substance Registry System :Thymidine, 3'-azido-3'-deoxy- (30516-87-1)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P311 Call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Zidovudine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC50 = 3 nM) with low cytotoxicity (CC50 > 5 μM). It is commonly used in combination therapy to slow the replication of HIV in vivo.

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