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SB-505124

SB-505124 Structure
  • ₹17860
  • Product name: SB-505124
  • CAS: 356559-13-2
  • MF: C20H22ClN3O2
  • MW: 371.87
  • EINECS:
  • MDL Number:
  • Synonyms:TGF-β RI Kinase Inhibitor III;Pyridine, 2-[5-(1,3-benzodioxol-5-yl)-2-(1,1-diMethylethyl)-1H-iMidazol-4-yl]-6-Methyl-, Monohydrochloride;SB-505124 hydrochloride;SB-505124 HCl;TGF-β RI Kinase Inhibitor III - CAS 356559-13-2 - Calbiochem;TGF-β RI Kinase Inhibitor III
Price1 Properties Safety Information Description
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Brand

  • Sigma-Aldrich(India)

Package

  • 2MG
  • ManufacturerSigma-Aldrich(India)
  • Product number616453
  • Product descriptionTGF-β RI Kinase Inhibitor III - CAS 356559-13-2 - Calbiochem The TGF-β RI Kinase Inhibitor III, also referenced under CAS 356559-13-2, controls the biological activity of TGF-β RI Kinase. This small molecule/inh
  • Packaging2MG
  • Price₹17860
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 616453 TGF-β RI Kinase Inhibitor III - CAS 356559-13-2 - Calbiochem The TGF-β RI Kinase Inhibitor III, also referenced under CAS 356559-13-2, controls the biological activity of TGF-β RI Kinase. This small molecule/inh 2MG ₹17860 2022-06-14 Buy

Properties

storage temp. :2-8°C
solubility :DMSO: 24 mg/mL
form :solid
color :yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

TGF-β RI Kinase Inhibitor III is a cell-permeable imidazolyl-pyridine compound that acts as a potent, ATP-competitive, reversible, and selective inhibitor of ACTR-IB (activin receptor-like kinase 4, IC50 = 129 nM), TGF β RI (activin receptor-like kinase 5, IC50 = 47 nM), and ACTR-IC (activin receptor-like kinase 7). TGF-β RI Kinase Inhibitor III inhibits p38 MAPKα only at much higher concentrations IC50 = 10.6 βM) and has little effect against ALK1/2/3/6 as well as a panel of 26 other kinases.

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Suppliers and manufacturers

Aladdin Scientific InvivoChem SIGMA-RBI Riedel-de Haen AG ApexBio Technology Shanghai Weiwei Biological Technology Co., Ltd. ShangHai Caerulum Pharma Discovery Co., Ltd. Aikon International Limited Suzhou yacoo science co.,Ltd MedBioPharmaceutical Technology Inc