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SINEFUNGIN

SINEFUNGIN Structure
  • ₹31257.6 - ₹67580.48
  • Product name: SINEFUNGIN
  • CAS: 58944-73-3
  • MF: C15H23N7O5
  • MW: 381.39
  • EINECS:637-385-5
  • MDL Number:MFCD00865623
  • Synonyms:6,7,8,9-hexadeoxy-yl)-5 ;6,9-diamino-1-(6-amino-9h-purin-9-d-glycero-alpha-l-talo-decofuranuronicaci ;6,9-diamino-1-(6-amino-9h-purin-9-yl)-1,5,6,7,8,9-hexadeoxydecofuranuronica ;compound57926 ;rp32232 ;SINEFUNGIN;5'-DEOXY-5'-(1,4-DIAMINO-4-CARBOXYBUTYL)ADENOSINE;ADENOSYLORNITHINE
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 10μG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSRP3251
  • Product descriptionSCF from rat recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
  • Packaging10μG
  • Price₹31257.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS8559
  • Product descriptionSinefungin 95% (HPLC), powder
  • Packaging10MG
  • Price₹67580.48
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SRP3251 SCF from rat recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture 10μG ₹31257.6 2022-06-14 Buy
Sigma-Aldrich(India) S8559 Sinefungin 95% (HPLC), powder 10MG ₹67580.48 2022-06-14 Buy

Properties

alpha :D25 -2.61° (c = 5 in water); D23 +12 ±2° (c = 0.227 in water)
Boiling point :783.2±70.0 °C(Predicted)
Density :1.91±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :H2O: soluble
form :powder
pka :pKa (66% DMF): 2.9, 3.9, 8.9, 10.2(at 25℃)
color :white to yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Sinefungin is a nucleoside structurally related to S-adenosylhomocysteine and S-adenosylmethionine that was originally isolated from Streptomyces. While it has limited use as an antibiotic due to its high in vivo toxicity, sinefungin has proved useful as a non-selective inhibitor of SET domain-containing methyltransferases in the study of epigenetic regulation (IC50 values range from 0.1-20 μM).

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