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ChemicalBook > Product Catalogue >Biochemical Engineering >Natural Products >Sinomenine

Sinomenine

Sinomenine Structure
  • ₹4449.08
  • Product name: Sinomenine
  • CAS: 115-53-7
  • MF: C19H23NO4
  • MW: 329.39
  • EINECS:204-094-6
  • MDL Number:MFCD00134303
  • Synonyms:SINOMENINE;(9alpha,13alpha,14alpha)-7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one;(9Alpha,13alpha,14alpha)-4-hydroxy-3,7-dimethoxy-17-methyl-7,8-didehydromorphinan-6-one hydrochlo;Sinomenine (9alpha,13alpha,14alpha)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one;Sinomenine 0.3 mol chloroform of crystallization;(9alpha,13alpha,14alpha)-4-hydroxy-3,7-dimethoxy-17-methyl-7,8-didehydromorphinan-6-one hydrochloride;Sinomenine, >=98%;Sinomenine/Sinomenine Hydrochloride
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Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • ManufacturerSigma-Aldrich(India)
  • Product number365602
  • Product descriptionSinomenine 0.3?mol chloroform of crystallization
  • Packaging100MG
  • Price₹4449.08
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 365602 Sinomenine 0.3?mol chloroform of crystallization 100MG ₹4449.08 2022-06-14 Buy

Properties

Melting point :180 °C (dec.)(lit.)
alpha :D26 -71° (c = 2.1 in alc)
Boiling point :466.98°C (rough estimate)
Density :1.2012 (rough estimate)
refractive index :1.5000 (estimate)
storage temp. :Store at +4°C
solubility :Soluble to 65 mg/mL (197.33 mM) in DMSO
pka :9.72±0.40(Predicted)
form :Solid
color :White to off-white
Merck :13,8620
InChIKey :YMEVIMJAUHZFMW-VUIDNZEBSA-N
LogP :1.245 (est)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Isolated by Ohta from Cocculus diversifolius DC., this alkaloid forms colourless crystals from MeOH. It is stated to possess a powerful reflex action and to be aspasm stimulant, finally causing paralysis and death in toxic doses. It is also said to suppress the hypotensive action of dihydroxyphenylethanolethylamine.

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