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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >Metformin

Metformin

Metformin Structure
  • ₹0
  • Product name: Metformin
  • CAS: 657-24-9
  • MF: C4H11N5
  • MW: 129.16
  • EINECS:211-517-8
  • MDL Number:MFCD00242652
  • Synonyms:1,1-dimethyl-biguanid ;dmgg ;flumamine ;gliguanid ;haurymelin ;la6023 ;melbin ;n,n-dimethylbiguanide
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :199-200 °C
Boiling point :229.23°C (rough estimate)
Density :1.0743 (rough estimate)
refractive index :1.5760 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :Acetonitrile (Slightly), Aqueous Acid (Slightly), Dichloromethane (Slightly)
form :Solid
pka :pKa 2.8(H2O,t =32) (Uncertain)
color :White to Light Brown
Water Solubility :Water: 50 mg/mL (387.12 mM)
BCS Class :3
InChI :InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)
InChIKey :XZWYZXLIPXDOLR-UHFFFAOYSA-N
SMILES :C(=N)(N(C)C)NC(=N)N
CAS DataBase Reference :657-24-9(CAS DataBase Reference)
EPA Substance Registry System :Imidodicarbonimidic diamide, N,N-dimethyl- (657-24-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

The study of metformin and its hypoglycemic effects originated from the study of goat’s rue plants, also known as Galega officinalis(French lilac). Goat’s rues are native plants in the Middle East and introduced to Europe later and have been used as forage and ornamental plants throughout the world, including China. As early as in the Middle Ages in Europe, it was found that goat’s rues could ease polyuria, which is one of the typical symptoms of diabetes. While goat’s rues were used to treat a variety of other diseases in the Middle Ages, it was found to cause poisoning symptoms in livestock. Goat’s rues are still used as medical plants at present, mainly for diabetes, diuretic, hepatoprotection, aiding in digestion and promoting lactation, etc. In China, goat’s rues were recorded first in the dictionary of Chinese seed plants and mainly used for the treatment of diabetes. However, because of high toxicity, it is rarely used in traditional Chinese medicines at present.

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Suppliers and manufacturers

J S LABS AARTIA KEM SCIENCE Sun Pharmaceutical Industries Ltd Smilax Laboratories Limited HRV Global Life Sciences Harman Finochem Ltd Besil Chem LLP Humble Healthcare Limited Wanbury Limited Syglak Laboratories Pvt Ltd