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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antiepileptic and anticonvulsant >Pregabalin

Pregabalin

Pregabalin Structure
  • ₹8053.8 - ₹52815.18
  • Product name: Pregabalin
  • CAS: 148553-50-8
  • MF: C8H17NO2
  • MW: 159.23
  • EINECS:604-639-1
  • MDL Number:MFCD00917044
  • Synonyms:PREGABALIN;(R)-Pregabalin;(S)-Pregabalin;(S)-3-(Ammoniomethyl)-5-methylhexanoate;3(S)-(AMINOMETHYL)-5;Pregabalin-13C3 RaceMic;PREGABALINE (S)-(+)-3-AMinoMethyl-5-Methylhexanoic acid;(S)-(+)-Pregabalin-d4
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 1ML
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML3167
  • Product descriptionPregabalin ≥95% (HPLC)
  • Packaging10MG
  • Price₹8053.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP-066
  • Product descriptionPregabalin solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹18659.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML3167
  • Product descriptionPregabalin ≥95% (HPLC)
  • Packaging50MG
  • Price₹32496.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP-120
  • Product descriptionPregabalin solution 10.0?mg/mL in water, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹52815.18
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML3167 Pregabalin ≥95% (HPLC) 10MG ₹8053.8 2022-06-14 Buy
Sigma-Aldrich(India) P-066 Pregabalin solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹18659.9 2022-06-14 Buy
Sigma-Aldrich(India) SML3167 Pregabalin ≥95% (HPLC) 50MG ₹32496.65 2022-06-14 Buy
Sigma-Aldrich(India) P-120 Pregabalin solution 10.0?mg/mL in water, ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹52815.18 2022-06-14 Buy

Properties

Melting point :194-196°C
alpha :D23 +10.52° (c = 1.06 in water)
Boiling point :274.0±23.0 °C(Predicted)
Density :0.997±0.06 g/cm3(Predicted)
Flash point :9℃
storage temp. :2-8°C
solubility :deionized water: ≥10mg/mL
pka :4.23±0.10(Predicted)
form :white powder
Water Solubility :Soluble to 100 mM in water
BCS Class :1
InChI :InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1
InChIKey :AYXYPKUFHZROOJ-ZETCQYMHSA-N
SMILES :C(O)(=O)C[C@@H](CN)CC(C)C
CAS DataBase Reference :148553-50-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Pregabalin (Lyrica), a derivative of GABA that is closely related to gabapentin, has undergone extensive research for its efficacy in treating conditions such as generalized anxiety disorder (GAD), fibromyalgia, neuropathic pain, and partial complex seizures. It seems to have a more targeted effect on the a2-δ subunit of calcium channels in the brain compared to gabapentin. Pregabalin was granted FDA approval at the end of 2004 for the treatment of neuropathic pain and epilepsy. In 2008, it became the first medication approved for the management of fibromyalgia. Although pregabalin was approved for GAD treatment in the European Union in 2006, it has not yet received FDA approval for GAD in the United States as of the time of writing.

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Suppliers and manufacturers

Jigs Chemical ltd Cadila Pharmaceuticals Ltd NILKANTH HEALTH CHEM (I) PRIVATE LIMITED ANWITA APIS Dr. Reddy's Laboratories Ltd ChemBioReas Life Sciences VASISTA LIFE SCIENCES PRIVATE LIMITED SGMR PHARMACEUTICALS PVT LTD ALMELO PRIVATE LIMITED THE MOLECULEZ