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SQ 22,536

SQ 22,536 Structure
  • ₹6300 - ₹82757.13
  • Product name: SQ 22,536
  • CAS: 17318-31-9
  • MF: C9H11N5O
  • MW: 205.22
  • EINECS:633-987-7
  • MDL Number:MFCD00210216
  • Synonyms:9-(2-tetrahydrofuryl)adenine;SQ 22,536 ADENYLATE CYCLASE INH;9-(Tetrahydro-2-furynal)-9H-purin-6-amine;SQ22,536/Inhibitor;9-(Tetrahydro-2-furanyl)-9H-purin-6-amine, 9-THF-Ade;6-Amino-9-[(tetrahydrofuran)-2-yl]-9H-purine;9-(Tetrahydrofuran-2-yl)-9H-purine-6-amine;6-Amino-9-(tetrahydro-2-furyl)-9H-purine
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 25MG
  • 50MG
  • ManufacturerTCI Chemicals (India)
  • Product numberQ0105
  • Product descriptionSQ 22536 min. 97.0 %
  • Packaging10MG
  • Price₹6300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberQ0105
  • Product descriptionSQ 22536 min. 97.0 %
  • Packaging50MG
  • Price₹14800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number568500
  • Product descriptionSQ 22536 - CAS 17318-31-9 - Calbiochem Cell-permeable adenylate cyclase inhibitor.
  • Packaging5MG
  • Price₹16670.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS153
  • Product descriptionSQ 22,536 ≥97% (HPLC), powder
  • Packaging5MG
  • Price₹21541.75
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS153
  • Product descriptionSQ 22,536 ≥97% (HPLC), powder
  • Packaging25MG
  • Price₹82757.13
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) Q0105 SQ 22536 min. 97.0 % 10MG ₹6300 2022-05-26 Buy
TCI Chemicals (India) Q0105 SQ 22536 min. 97.0 % 50MG ₹14800 2022-05-26 Buy
Sigma-Aldrich(India) 568500 SQ 22536 - CAS 17318-31-9 - Calbiochem Cell-permeable adenylate cyclase inhibitor. 5MG ₹16670.01 2022-06-14 Buy
Sigma-Aldrich(India) S153 SQ 22,536 ≥97% (HPLC), powder 5MG ₹21541.75 2022-06-14 Buy
Sigma-Aldrich(India) S153 SQ 22,536 ≥97% (HPLC), powder 25MG ₹82757.13 2022-06-14 Buy

Properties

Melting point :160-161℃
Boiling point :474.8±55.0 °C(Predicted)
Density :1.70±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :H2O: 21 mg/mL
form :solid
pka :3.82±0.10(Predicted)
color :white to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

SQ 22,536 is an inhibitor of adenylyl cyclase with an IC50 value of 13 μM for inhibition of prostaglandin E1-stimulated increase in cAMP in intact platelets. It has been used to evaluate adenylyl cyclase activity during iloprost-induced vasorelaxation of isolated pulmonary veins or aorta in several research paradigms, inhibiting cAMP elevation at concentrations of 100-300 μM without effecting relaxation.

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