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SR3335

SR3335 Structure
  • ₹8400.2 - ₹33914.73
  • Product name: SR3335
  • CAS: 293753-05-6
  • MF: C13H9F6NO3S2
  • MW: 405.3358792
  • EINECS:
  • MDL Number:MFCD02724814
  • Synonyms:SR3335;SR3335,Thiophene-2-sulfonic acid [4-(2,2,2-trifluoro-1-hydroxy-1-trifluoroMethyl-ethyl)-phenyl]-aMide;ML-176;N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide;hiophene-2-sulfonic acid [4-(2,2,2-trifluoro-1-hydroxy-1-trifluoroMethyl-ethyl)-phenyl]-aMide;ML-176;SR-3335;SR3335;ML-176;SR 3335;SR-3335;ML176;ML 176;SR3335;ML176
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML2820
  • Product descriptionSR3335 ≥98% (HPLC)
  • Packaging25MG
  • Price₹33914.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML2820
  • Product descriptionSR3335 ≥98% (HPLC)
  • Packaging5MG
  • Price₹8400.2
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML2820 SR3335 ≥98% (HPLC) 25MG ₹33914.73 2022-06-14 Buy
Sigma-Aldrich(India) SML2820 SR3335 ≥98% (HPLC) 5MG ₹8400.2 2022-06-14 Buy

Properties

storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :insoluble in H2O; ≥87.4 mg/mL in EtOH; ≥88.8 mg/mL in DMSO
form :solid
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

The retinoic acid receptor-related receptors (RORs) are orphan nuclear receptors with diverse putative roles. SR 3335 is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki = 220 nM) and inhibiting constitutive transactivation activity (IC50 = 480 nM). It is without effect on RORβ, RORγ, farnesoid X receptor, or liver X receptor α. SR 3335 evokes RORα-dependent effects both in vitro and in vivo, altering gene expression as well as gluconeogenesis.