Suramin sodium
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- ₹4589.99 - ₹14559.63
- Product name: Suramin sodium
- CAS: 129-46-4
- MF: C51H34N6Na6O23S6
- MW: 1429.17
- EINECS:204-949-3
- MDL Number:MFCD00210217
- Synonyms:sodiumsuramin ;SURAMIN SODIUM, 98+%;8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfoni;8-[[4-Methyl-3-[[3-[[3-[[2-methyl-5-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonic acid;F-309;Naganol;Suramin hexasodium salt,98%;Suppressor
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 25MG
- 50MG
- 100MG
- ManufacturerSigma-Aldrich(India)
- Product number574625
- Product descriptionSuramin, Sodium Salt - CAS 129-46-4 - Calbiochem A reversible and competitive inhibitor of protein tyrosine phosphatases.
- Packaging50MG
- Price₹4589.99
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS2671
- Product descriptionSuramin sodium salt ≥98% (TLC)
- Packaging25MG
- Price₹8595.05
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS2671
- Product descriptionSuramin sodium salt ≥98% (TLC)
- Packaging100MG
- Price₹14559.63
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 574625 | Suramin, Sodium Salt - CAS 129-46-4 - Calbiochem A reversible and competitive inhibitor of protein tyrosine phosphatases. | 50MG | ₹4589.99 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S2671 | Suramin sodium salt ≥98% (TLC) | 25MG | ₹8595.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S2671 | Suramin sodium salt ≥98% (TLC) | 100MG | ₹14559.63 | 2022-06-14 | Buy |
Properties
Melting point :>260°C (dec.)
storage temp. :0-6°C
solubility :H2O: >10mg/mL
form :Crystalline Powder
color :White
PH :pH(10g/l, 25℃) : 5.0～8.0
Water Solubility :soluble
BRN :3694087
Stability :Hygroscopic
InChIKey :VAPNKLKDKUDFHK-UHFFFAOYSA-H
storage temp. :0-6°C
solubility :H2O: >10mg/mL
form :Crystalline Powder
color :White
PH :pH(10g/l, 25℃) : 5.0～8.0
Water Solubility :soluble
BRN :3694087
Stability :Hygroscopic
InChIKey :VAPNKLKDKUDFHK-UHFFFAOYSA-H
Safety Information
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| Signal word: | Warning | ||||||||||||||||
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Description
Suramin is a polysulfonated naphthylurea that inhibits the binding of calmodulin to recognition sites on the ryanodine receptor-1 (IC50 = 4.9 μM), blocks G protein coupling to GPCRs, and non-selectively antagonizes P2 purinergic receptors (10-100 μM). Suramin also acts as a non-specific competitor of glycosaminoglycan binding to a variety of targets including TGFβ, PDGF, and FGF and additionally inhibits insulin-like growth factor-l, EGF, PKC activity, TNF, IL-2, transferrin, and Apo-B. While originally used as an early stage treatment of trypanosome-caused onchocerciasis (African river blindness) and African trypanosomiasis (African sleeping sickness), suramin has been under clinical evaluation for its potential to regress a number of cancer cell lines, including non-small cell lung cancer, advanced breast cancer, hormone refractory prostate cancer, metastatic renal cell cancer, colorectal cancer, and high-grade gliomas.More related product prices
Methyl salicylate TRI-O-TOLYLPHOSPHINE Tribenuron methyl 1,5-Diphenylcarbazide Methyl acetate Sodium hydroxide Sodium chloride Sodium benzoate Pirimiphos-methyl 74223-64-6 2-Methylnaphthalene Sodium chlorite Sodium sulfate Sodium acetate Chlorodimethylphenylsilane Sodium bicarbonate Diclofenac sodium Kresoxim-methylRelated product price
- Methyl salicylate
₹990-179240.35 - TRI-O-TOLYLPHOSPHINE
₹2379-16855 - Tribenuron methyl
₹7869.78
