Tamibarotene
- ₹10857.48 - ₹39771.05
- Product name: Tamibarotene
- CAS: 94497-51-5
- MF: C22H25NO3
- MW: 351.44
- EINECS:1806241-263-5
- MDL Number:MFCD00866188
- Synonyms:AM80;Tamibarotene;4-[(5,5,8,8-Tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid;4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]benzoic Acid;Am 80 (pharmaceutical);Amnolake;NSC 608000;Retinoid AM 80
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberT3205
- Product descriptionTamibarotene ≥98% (HPLC)
- Packaging5MG
- Price₹10857.48
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT3205
- Product descriptionTamibarotene ≥98% (HPLC)
- Packaging25MG
- Price₹39771.05
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | T3205 | Tamibarotene ≥98% (HPLC) | 5MG | ₹10857.48 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | T3205 | Tamibarotene ≥98% (HPLC) | 25MG | ₹39771.05 | 2022-06-14 | Buy |
Properties
Melting point :231-232°C
Boiling point :449.6±45.0 °C(Predicted)
Density :1.154±0.06 g/cm3(Predicted)
RTECS :DH6940000
storage temp. :room temp
solubility :Soluble to 50 mM in DMSO
form :powder
pka :3.83±0.10(Predicted)
color :white to off-white
Boiling point :449.6±45.0 °C(Predicted)
Density :1.154±0.06 g/cm3(Predicted)
RTECS :DH6940000
storage temp. :room temp
solubility :Soluble to 50 mM in DMSO
form :powder
pka :3.83±0.10(Predicted)
color :white to off-white
Safety Information
Symbol(GHS): | ||||||||
---|---|---|---|---|---|---|---|---|
Signal word: | ||||||||
Hazard statements: |
|
|||||||
Precautionary statements: |
|
Description
Tamibarotene (brand name: Amnolake) is a kind of orally administrated synthetic retinoid. It is used to overcome the all- trans retinoid acid (ATRA) resistance, having potential antineoplastic activity against the acute promyelocytic leukaemia (APL). It can also be used for the treatment of Alzheimer's disease, multiple myeloma and Crohn's disease. Tamibarotene takes effect through directly acting as the specific agonist for retinoid acid receptor alpha/beta, and potentially binding to the retinoid X receptors (RXR). Compared to the ATRA, Tamibarotene is chemically more stable and much more potent as an inducer of differentiation and apoptosis in promyelocytic leukemia cells.Related product price
- Glycine
₹280-116823.4 - 4-Aminobenzoic acid
₹600-32182.73 - Folic acid
₹260-31316.73