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TBBZ

TBBZ Structure
  • ₹15761.2 - ₹63250.48
  • Product name: TBBZ
  • CAS: 577779-57-8
  • MF: C7H2Br4N2
  • MW: 433.72
  • EINECS:
  • MDL Number:MFCD04116202
  • Synonyms:4,5,6,7-tetrabromo-1H-benzimidazole;4,5,6,7-tetrabromo-1H-benzo[d]imidazole;4,5,6,7-tetrabromo-1H-benzo[d]imidazole(WXC06733);1H-Benzimidazole, 4,5,6,7-tetrabromo-
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 20MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6951
  • Product descriptionTBBz ≥98% (HPLC), powder
  • Packaging5MG
  • Price₹15761.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number5.05766
  • Product descriptionCasein Kinase II Inhibitor XII, TBBz - CAS 577779-57-8 - Calbiochem
  • Packaging20MG
  • Price₹24770.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6951
  • Product descriptionTBBz ≥98% (HPLC), powder
  • Packaging25MG
  • Price₹63250.48
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) T6951 TBBz ≥98% (HPLC), powder 5MG ₹15761.2 2022-06-14 Buy
Sigma-Aldrich(India) 5.05766 Casein Kinase II Inhibitor XII, TBBz - CAS 577779-57-8 - Calbiochem 20MG ₹24770.01 2022-06-14 Buy
Sigma-Aldrich(India) T6951 TBBz ≥98% (HPLC), powder 25MG ₹63250.48 2022-06-14 Buy

Properties

Melting point :330-332°C
Boiling point :553.5±45.0 °C(Predicted)
Density :2.713±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL at 60°C, clear
form :powder
pka :6.73±0.30(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Casein kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis, and its activity is increased in many proliferating tissues and tumors. 4,5,6,7-Tetrabromobenzimidazole is a selective, ATP-competitive inhibitor of CK2 with Ki values ranging from 0.5-1 μM in rat liver, S. cerevisiae, C. tropicalis, and N. crassa. It is inactive against PKA and PKC and a relatively weak inhibitor of CK1 (Ki = 54.4-64.2 μM).

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Suppliers and manufacturers

CLEARSYNTH LABS LTD.
Labnetwork lnc. Shanghai Kaiwei Chemical Technology Co., Ltd. Aikon International Limited DC Chemicals Beijing Stronger Science Co., Ltd. Henan Lien Chemical Products Co., Ltd. Shanghai Haohong Scientific Co., Ltd. MedBioPharmaceutical Technology Inc Suzhou Meishi Biotechnology Co., Ltd.