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tert-Butyl rosuvastatin

tert-Butyl rosuvastatin Structure
  • ₹0
  • Product name: tert-Butyl rosuvastatin
  • CAS: 355806-00-7
  • MF: C26H36FN3O6S
  • MW: 537.64
  • EINECS:609-144-4
  • MDL Number:MFCD08460212
  • Synonyms:(+)-(3R, 5S)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYL-N-METHANESULFONYLAMINO)PYRIMIDIN-5-YL]-(3, 5)-DIHYDROXY-6(E)-HEPTENOATE;Rosuvastatin intermediate R-3 ;tert-Butyl(+)-(3R,5S)-7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methanesul fonylamino)pyrimidin-5-yl]-3,5-Dihydroxy-6(E)-Heptenoate;ZD-8;Tert-butyl-(+)7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N- methylsulfonylamino)pyrimidine-5-yl] -(3R,5S) -dihydroxy -(E)-6-Heptena;Tert-butyl-(+)7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidine-5-yl]-(3R,5S)-dihydroxy;(3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-Methylethyl)]-2-[Methyl(Methylsulfonyl)aMino-5-pyriMidinyl]-3,5-dihydroxy-6-heptenoicacidtert-butylester;T-BUTYL 7-[4-(4-FLUOROPHENYL)-6-ISO-PROPYL-2-(N-METHYL-N-METHYLSULFONYLAMINO)PYRIMIDIN-5-YL] -(3R,5S)-DIHYDROXY-(E)-6-HEPTENATE
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :136-138oC
Boiling point :704.2±70.0 °C(Predicted)
Density :1.259
storage temp. :Sealed in dry,Room Temperature
solubility :Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
pka :13.38±0.20(Predicted)
form :Solid
color :White to Off-White
Stability :Hygroscopic
CAS DataBase Reference :355806-00-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

tert-Butyl Rosuvastatin is an impurity of Rosuvastatin (287714-41-4 #CAS), which is a HMG-?CoA reductase inhibitor. In combination of pemafibrate or a salt, it can function as cardiovascular disease medication.

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