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Tomatidine hydrochloride

Tomatidine hydrochloride Structure
  • ₹7036.25 - ₹20578.33
  • Product name: Tomatidine hydrochloride
  • CAS: 6192-62-7
  • MF: C27H46ClNO2
  • MW: 452.11
  • EINECS:
  • MDL Number:MFCD11521518
  • Synonyms:3BETA-HYDROXY-5ALPHA-TOMATIDANE HYDROCHLORIDE;5ALPHA-TOMATIDAN-3BETA-OL HYDROCHLORIDE;TOMATIDINE HCL;TOMATIDINE HYDROCHLORIDE;SPIRPSOLAN-3-OL-(3B,5A,22B,25C) HCL;(3beta,5alpha,22beta,25S)-Spirosolan-3-ol hydrochloride;TOMATIDINE HCL(RG);Tomatidine, Hydrochloride, >85%
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 25MG
  • 100MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2909
  • Product descriptionTomatidine hydrochloride ≥85%
  • Packaging25MG
  • Price₹7036.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number614350
  • Product descriptionTomatidine, HCl - CAS 6192-62-7 - Calbiochem A steroidal alkaloid that structurally resembles Cyclopamine, but lacks the capacity to inhibit Shh (Sonic Hedgehog) signaling. Reported to be non-ter
  • Packaging25MG
  • Price₹9490
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2909
  • Product descriptionTomatidine hydrochloride ≥85%
  • Packaging100MG
  • Price₹20578.33
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) T2909 Tomatidine hydrochloride ≥85% 25MG ₹7036.25 2022-06-14 Buy
Sigma-Aldrich(India) 614350 Tomatidine, HCl - CAS 6192-62-7 - Calbiochem A steroidal alkaloid that structurally resembles Cyclopamine, but lacks the capacity to inhibit Shh (Sonic Hedgehog) signaling. Reported to be non-ter 25MG ₹9490 2022-06-14 Buy
Sigma-Aldrich(India) T2909 Tomatidine hydrochloride ≥85% 100MG ₹20578.33 2022-06-14 Buy

Properties

Melting point :281-284°C (dec.)
storage temp. :2-8°C
solubility :Methanol (Slightly)
form :Off-white solid
color :White to Off-White
BRN :3920740

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Tomatidine is a steroidal alkaloid found in skins and leaves of tomatoes. It has been shown to suppress NF-κB signaling in LPS-stimulated macrophages, blocking induced expression of iNOS and COX-2. It is a reported functional inhibitor of acid sphingomyelinase. Tomatidine also has antibacterial properties, blocking the replication of S. aureus variants that are pathogenic in cystic fibrosis more potently than normal strains (MICs = 0.12 and >16 μg/ml, respectively). It prevents skeletal muscle atrophy associated with fasting or spinal cord injury in mice. Tomatidine has also been used as a negative control for cyclopamine in studies involving signaling mediated by the hedgehog pathway.

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