Vadimezan
|
- ₹7300 - ₹80743.68
- Product name: Vadimezan
- CAS: 117570-53-3
- MF: C17H14O4
- MW: 282.29
- EINECS:700-141-4
- MDL Number:MFCD00870555
- Synonyms:5,6-dimethylxanthenoneacetic acid;DMXAA;vadimezan;(5,6-DIMETHYL-9-OXO-XANTHEN)-4-ACETIC ACID;5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acid;5,6-Dimethylxanthenone-4-acetic acid;NSC-640488;NSC-649488
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- 50MG
- 250MG
- ManufacturerTCI Chemicals (India)
- Product numberD5235
- Product descriptionVadimezan
- Packaging50MG
- Price₹7300
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberD5235
- Product descriptionVadimezan
- Packaging250MG
- Price₹19900
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD5817
- Product descriptionDMXAA ≥98% (HPLC), solid
- Packaging5MG
- Price₹20405.13
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD5817
- Product descriptionDMXAA ≥98% (HPLC), solid
- Packaging25MG
- Price₹80743.68
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | D5235 | Vadimezan | 50MG | ₹7300 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D5235 | Vadimezan | 250MG | ₹19900 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | D5817 | DMXAA ≥98% (HPLC), solid | 5MG | ₹20405.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D5817 | DMXAA ≥98% (HPLC), solid | 25MG | ₹80743.68 | 2022-06-14 | Buy |
Properties
Melting point :259-261 °C
Boiling point :520.9±50.0 °C(Predicted)
Density :1.321±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20℃
storage temp. :2-8°C
solubility :DMSO: 17 mg/mL, soluble
form :solid
pka :4.21±0.10(Predicted)
color :light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
Boiling point :520.9±50.0 °C(Predicted)
Density :1.321±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20℃
storage temp. :2-8°C
solubility :DMSO: 17 mg/mL, soluble
form :solid
pka :4.21±0.10(Predicted)
color :light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
DMXAA is a xanthene which acts as a tumor vascular disrupting agent, inducing apoptosis in tumor vascular endothelium resulting in necrosis at the tumor core. It potently activates the TANK-binding kinase 1-interferon regulatory factor 3 (TBK1/IRF3) signaling pathway in leukocytes, inducing type-I-interferon (IFN) production. Specifically, DMXAA activates the mitochondria- and endoplasmic reticulum-associated protein known as stimulator of interferon genes (STING), leading to TBK1/IRF3 signaling. DMXAA signals through mouse STING but not human STING. In addition, DMXAA significantly inhibits several kinases in endothelial cells, including the vascular endothelial growth factor (VEGF) receptors VEGFR1 and VEGFR2 (IC50 = 119 and 11 μM, respectively).Related product price
- N,N-Dimethylformamide
₹480-928440 - Poly(dimethylsiloxane)
₹102-38959.18 - Dimethyl sulfoxide
₹802.14-1456730.01
