XCT 790

₹20643.28 - ₹78946.73
Product name: XCT 790
CAS: 725247-18-7
MF: C23H13F9N4O3S
MW: 596.42
EINECS:
MDL Number:MFCD08277031
Synonyms:3-[4-(2,4-bis-trifluoromethylbenzyloxy)-3-methoxyphenyl]-2-cyano-n-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)acrylamide;3-[4-[[2,4-Bis(trifluoromethyl)benzyl]oxy]-3-methoxyphenyl]-2-cyano-N-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)acrylamide XCT 790;XCT 790 3-[4-[[2,4-Bis(trifluoromethyl)benzyl]oxy]-3-methoxyphenyl]-2-cyano-N-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)acrylamide;(E)-3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]prop-2-enamide;XCT 790; XCT-790;CS-1881;2-Propenamide, 3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-;XCT 790,Inhibitor,Estrogen Receptor/ERR,Autophagy,XCT790,inhibit,XCT-790

Price2 Properties Safety Information Description

2 prices

Selected condition：

Brand

Sigma-Aldrich(India)

Package

5MG
25MG

ManufacturerSigma-Aldrich(India)
Product numberX4753
Product descriptionXCT790 ≥98% (HPLC), solid
Packaging25MG
Price₹78946.73
Updated2022-06-14
Buy

ManufacturerSigma-Aldrich(India)
Product numberX4753
Product descriptionXCT790 ≥98% (HPLC), solid
Packaging5MG
Price₹20643.28
Updated2022-06-14
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	X4753	XCT790 ≥98% (HPLC), solid	25MG	₹78946.73	2022-06-14	Buy
Sigma-Aldrich(India)	X4753	XCT790 ≥98% (HPLC), solid	5MG	₹20643.28	2022-06-14	Buy

Properties

storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
form :solid
color :yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning		P264, P270, P301+P312, P330, P501
H413	May cause long lasting harmful effects to aquatic life	Hazardous to the aquatic environment, long-term hazard	Category 4

Precautionary statements:

P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P273	Avoid release to the environment.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330	Rinse mouth.

Description

XCT790 is an inverse agonist of estrogen-related receptor α (ERRα; IC50 = ~300-500 nM). It demonstrates 90-100% inhibition of ERRα constitutive activity and has no significant activity at related nuclear receptors at 10 μM. XCT790 associates with the ligand-binding domain of ERRα and blocks ERRα/PGC-1α-dependent signaling, suppressing the expression of monoamine oxidases A and B. XCT790 induces proteasomal degradation of ERRα and potentiates the degradation of the estrogen receptor ERα by fulvestrant .

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