2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide
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- $23 - $1530
- Product name: 2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide
- CAS: 108605-62-5
- MF: C12H9F3N2O2
- MW: 270.21
- EINECS:1308068-626-2
- MDL Number:MFCD00910058
- Synonyms:A77 1726;N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide, LEF-M;(2Z)-2-[hydroxy-[[4-(trifluoromethyl)phenyl]amino]methylidene]-3-oxo-butanenitrile;2-Cyano-3OH-N-(4-trifluoromethylphenyl) crotonamide-d4;IMp. A (EP) as Hydrochloride: 4-(TrifluoroMethyl)aniline Hydrochloride;TeriflunoMide, A77 1726;2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide;2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide
28 prices
Selected condition：
Brand
- AHH
- AK Scientific
- Ambeed
- ApexBio Technology
- AvaChem
- Biorbyt Ltd
- Chemenu
- Crysdot
- CSNpharm
- Labseeker
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 20mg
- 0.025g
- 50
- 25mg
- 50MG
- 100mg
- 250mg
- 500mg
- 1g
- 5g
- 10g
- ManufacturerAHH
- Product numberMT-07007
- Product description2-Cyano-3-OH-N-(4-trifluoromethylphenyl)crotonamide 98%
- Packaging0.025g
- Price$379
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1709AA
- Product description2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide
- Packaging25mg
- Price$107
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1709AA
- Product description2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide
- Packaging100mg
- Price$163
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1709AA
- Product description2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide
- Packaging250mg
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1709AA
- Product description2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide
- Packaging1g
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA132118
- Product descriptionTeriflunomide(RandomConfiguration) 99+%
- Packaging25mg
- Price$23
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA132118
- Product descriptionTeriflunomide(RandomConfiguration) 99+%
- Packaging100mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA132118
- Product descriptionTeriflunomide(RandomConfiguration) 99+%
- Packaging250mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA132118
- Product descriptionTeriflunomide(RandomConfiguration) 99+%
- Packaging1g
- Price$222
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA132118
- Product descriptionTeriflunomide(RandomConfiguration) 99+%
- Packaging5g
- Price$448
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1850
- Product descriptionTeriflunomide
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3802
- Product description2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)-crotoneamide
- Packaging5mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3802
- Product description2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)-crotoneamide
- Packaging10mg
- Price$325
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3802
- Product description2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)-crotoneamide
- Packaging25mg
- Price$625
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146201
- Product descriptionTeriflunomide (A-771726) >98%
- Packaging1g
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM128597
- Product description(Z)-2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide 95+%
- Packaging1g
- Price$327
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-07007 | 2-Cyano-3-OH-N-(4-trifluoromethylphenyl)crotonamide 98% | 0.025g | $379 | 2021-12-16 | Buy |
| AK Scientific | 1709AA | 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide | 25mg | $107 | 2021-12-16 | Buy |
| AK Scientific | 1709AA | 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide | 100mg | $163 | 2021-12-16 | Buy |
| AK Scientific | 1709AA | 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide | 250mg | $230 | 2021-12-16 | Buy |
| AK Scientific | 1709AA | 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide | 1g | $500 | 2021-12-16 | Buy |
| Ambeed | A132118 | Teriflunomide(RandomConfiguration) 99+% | 25mg | $23 | 2021-12-16 | Buy |
| Ambeed | A132118 | Teriflunomide(RandomConfiguration) 99+% | 100mg | $60 | 2021-12-16 | Buy |
| Ambeed | A132118 | Teriflunomide(RandomConfiguration) 99+% | 250mg | $90 | 2021-12-16 | Buy |
| Ambeed | A132118 | Teriflunomide(RandomConfiguration) 99+% | 1g | $222 | 2021-12-16 | Buy |
| Ambeed | A132118 | Teriflunomide(RandomConfiguration) 99+% | 5g | $448 | 2021-12-16 | Buy |
| ApexBio Technology | B1850 | Teriflunomide | 10mg | $50 | 2021-12-16 | Buy |
| AvaChem | 3802 | 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)-crotoneamide | 5mg | $175 | 2021-12-16 | Buy |
| AvaChem | 3802 | 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)-crotoneamide | 10mg | $325 | 2021-12-16 | Buy |
| AvaChem | 3802 | 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)-crotoneamide | 25mg | $625 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146201 | Teriflunomide (A-771726) >98% | 1g | $765 | 2021-12-16 | Buy |
| Chemenu | CM128597 | (Z)-2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide 95+% | 1g | $327 | 2021-12-16 | Buy |
Properties
Melting point :229-232°C
Boiling point :410.8±45.0 °C(Predicted)
Density :1.424±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 5 mg/ml with warming).
form :Solid
pka :5.20±0.50(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :410.8±45.0 °C(Predicted)
Density :1.424±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 5 mg/ml with warming).
form :Solid
pka :5.20±0.50(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Teriflunomide (Aubagio®), also known as A77 1726, is an immunosupressant marketed by Sanofi for the teatment of multiple sclerosis (MS). Teriflunomide is the active metabolite of leflunomide, used for treatment of patients diagnosed with rheumatoid arthritis, and therefore simultaneously can be used as a treatment for rheumatoid arthritis.Teriflunomide acts as an inhibitor of the mitochondrial enzyme dihydrorotate dehydrogenase, inhibiting pyrimidine formation, and resulting in reduced B and T cell proliferation.Related product price
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