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ChemicalBook >> CAS DataBase List >> ARP100

ARP100

ARP100 price.
  • $29 - $3361
  • Product name: ARP100
  • CAS: 704888-90-4
  • MF: C17H20N2O5S
  • MW: 364.42
  • EINECS:
  • MDL Number:MFCD09971105
  • Synonyms:ARP100;N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)acetamide;2-[((1,1'-Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide;MMP-2 Inhibitor III;N-hydroxy-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]acetamide;Acetamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-;N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide;metalloproteinase,Inhibitor,Matrix metalloproteinases,selective,matrigel,ARP 100,matrix,invasion,ARP100,anti-invasive,MMP,ARP-100,inhibit
Price18 Properties Safety Information Description
18 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5
  • 1MG
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number0914AC
  • Product descriptionN-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide
  • Packaging10mg
  • Price$305
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64151
  • Product descriptionARP 100
  • Packaging5mg
  • Price$83.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA443997
  • Product descriptionN-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 95+%
  • Packaging50mg
  • Price$654
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA443997
  • Product descriptionN-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 95+%
  • Packaging100mg
  • Price$954
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA443997
  • Product descriptionN-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 95+%
  • Packaging250mg
  • Price$1431
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA443997
  • Product descriptionN-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 95+%
  • Packaging1g
  • Price$3361
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0002644
  • Product description2-[((1,1'-BIPHENYL)-4-YL-SULFONYL)-(1-METHYLETHOXY)AMINO]-N-HYDROXYACETAMIDE 95.00%
  • Packaging1MG
  • Price$132.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0002644
  • Product description2-[((1,1'-BIPHENYL)-4-YL-SULFONYL)-(1-METHYLETHOXY)AMINO]-N-HYDROXYACETAMIDE 95.00%
  • Packaging5MG
  • Price$501.73
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4432
  • Product descriptionARP 100
  • Packaging5mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4432
  • Product descriptionARP 100
  • Packaging10mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13321
  • Product descriptionARP 100 ≥98%
  • Packaging1mg
  • Price$29
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13321
  • Product descriptionARP 100 ≥98%
  • Packaging5mg
  • Price$104
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13321
  • Product descriptionARP 100 ≥98%
  • Packaging10mg
  • Price$186
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0027901
  • Product descriptionARP 100 >99.0%
  • Packaging10mg
  • Price$630
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number444288
  • Product descriptionMMP-2 Inhibitor III - CAS 704888-90-4 - Calbiochem
  • Packaging5mg
  • Price$332
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number2621
  • Product descriptionARP 100 ≥99%(HPLC)
  • Packaging5
  • Price$149
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0914AC N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 10mg $305 2021-12-16 Buy
Alfa Aesar J64151 ARP 100 5mg $83.9 2021-12-16 Buy
Ambeed A443997 N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 95+% 50mg $654 2021-12-16 Buy
Ambeed A443997 N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 95+% 100mg $954 2021-12-16 Buy
Ambeed A443997 N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 95+% 250mg $1431 2021-12-16 Buy
Ambeed A443997 N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 95+% 1g $3361 2021-12-16 Buy
American Custom Chemicals Corporation INB0002644 2-[((1,1'-BIPHENYL)-4-YL-SULFONYL)-(1-METHYLETHOXY)AMINO]-N-HYDROXYACETAMIDE 95.00% 1MG $132.3 2021-12-16 Buy
American Custom Chemicals Corporation INB0002644 2-[((1,1'-BIPHENYL)-4-YL-SULFONYL)-(1-METHYLETHOXY)AMINO]-N-HYDROXYACETAMIDE 95.00% 5MG $501.73 2021-12-16 Buy
ApexBio Technology A4432 ARP 100 5mg $116 2021-12-16 Buy
ApexBio Technology A4432 ARP 100 10mg $210 2021-12-16 Buy
Cayman Chemical 13321 ARP 100 ≥98% 1mg $29 2024-03-01 Buy
Cayman Chemical 13321 ARP 100 ≥98% 5mg $104 2024-03-01 Buy
Cayman Chemical 13321 ARP 100 ≥98% 10mg $186 2024-03-01 Buy
ChemScene CS-0027901 ARP 100 >99.0% 10mg $630 2021-12-16 Buy
Sigma-Aldrich 444288 MMP-2 Inhibitor III - CAS 704888-90-4 - Calbiochem 5mg $332 2024-03-01 Buy
Tocris 2621 ARP 100 ≥99%(HPLC) 5 $149 2021-12-16 Buy
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Properties

storage temp. :Desiccate at +4°C
solubility :Soluble at 100mM in DMSO
form :Solid
color :Off-white to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. During cancer progression both MMP-2 and MMP-9 play a role in metastatic tumor dispersion and angiogenesis. ARP 100 is a biphenylsulfonamide that acts as a selective inhibitor of MMP-2 demonstrating an IC50 value of 12 nM. Due to its specific zinc binding domain configuration, the inhibitory activity of ARP 100 is significantly less potent towards MMP-1, MMP-3, MMP-7, and MMP-9 (IC50 values are 50, 4.5, 50, and 2 μM, respectively). At 50 nM, ARP 100 suppresses the invasive behavior of HT1080 tumor cells grown on matrigel.

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Aladdin Scientific 3B Pharmachem (Wuhan) International Co.,Ltd. Alabiochem Tech.Co., Ltd. VDM Biochemicals AdooQ BioScience, LLC