SANT-1
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- $55 - $1593.9
- Product name: SANT-1
- CAS: 304909-07-7
- MF: C23H27N5
- MW: 373.49
- EINECS:
- MDL Number:MFCD01827306
- Synonyms:N-[(3,5-DIMETHYL-1-PHENYL-1H-PYRAZOL-4-YL)METHYLENE]-4-(PHENYLMETHYL)-1-PIPERAZINAMINE;SANT-1;(4-Benzyl-piperazin-1-yl)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-ylmethylene)-amine;1-Piperazinamine, N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-;(E)-N-(4-benzylpiperazin-1-yl)-1-(3,5-dimethyl-1-phenylpyrazol-4-yl)methanimine;SANT1 10MG;SANT1;SANT 1;SANT-1 - CAS 304909-07-7 - Calbiochem
20 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
Package
- 1MG
- 5mg
- 10mg
- 25mg
- 50mg
- 250mg
- 1g
- 100MG
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number2700AH
- Product descriptionSANT-1
- Packaging10mg
- Price$196
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ65294
- Product descriptionSANT-1
- Packaging10mg
- Price$169
- Updated2023-06-20
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000824
- Product descriptionSANT-1 95.00%
- Packaging1MG
- Price$165.9
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000824
- Product descriptionSANT-1 95.00%
- Packaging10MG
- Price$704.55
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000824
- Product descriptionSANT-1 95.00%
- Packaging100MG
- Price$1593.9
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8659
- Product descriptionSANT-1
- Packaging10mM(in 1mL DMSO)
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8659
- Product descriptionSANT-1
- Packaging10mg
- Price$103
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8659
- Product descriptionSANT-1
- Packaging50mg
- Price$399
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14933
- Product descriptionSANT 1 ≥98%
- Packaging1mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14933
- Product descriptionSANT 1 ≥98%
- Packaging5mg
- Price$107
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14933
- Product descriptionSANT 1 ≥98%
- Packaging10mg
- Price$168
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0018354
- Product descriptionSANT-1 99.85%
- Packaging5mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0018354
- Product descriptionSANT-1 99.85%
- Packaging10mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0018354
- Product descriptionSANT-1 99.85%
- Packaging50mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0018354
- Product descriptionSANT-1 99.85%
- Packaging100mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8327
- Product descriptionSANT-1 >98%
- Packaging250mg
- Price$750
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2700AH | SANT-1 | 10mg | $196 | 2021-12-16 | Buy |
| Alfa Aesar | J65294 | SANT-1 | 10mg | $169 | 2023-06-20 | Buy |
| American Custom Chemicals Corporation | API0000824 | SANT-1 95.00% | 1MG | $165.9 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0000824 | SANT-1 95.00% | 10MG | $704.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0000824 | SANT-1 95.00% | 100MG | $1593.9 | 2021-12-16 | Buy |
| ApexBio Technology | A8659 | SANT-1 | 10mM(in 1mL DMSO) | $80 | 2021-12-16 | Buy |
| ApexBio Technology | A8659 | SANT-1 | 10mg | $103 | 2021-12-16 | Buy |
| ApexBio Technology | A8659 | SANT-1 | 50mg | $399 | 2021-12-16 | Buy |
| Cayman Chemical | 14933 | SANT 1 ≥98% | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 14933 | SANT 1 ≥98% | 5mg | $107 | 2024-03-01 | Buy |
| Cayman Chemical | 14933 | SANT 1 ≥98% | 10mg | $168 | 2024-03-01 | Buy |
| ChemScene | CS-0018354 | SANT-1 99.85% | 5mg | $55 | 2021-12-16 | Buy |
| ChemScene | CS-0018354 | SANT-1 99.85% | 10mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-0018354 | SANT-1 99.85% | 50mg | $250 | 2021-12-16 | Buy |
| ChemScene | CS-0018354 | SANT-1 99.85% | 100mg | $450 | 2021-12-16 | Buy |
| DC Chemicals | DC8327 | SANT-1 >98% | 250mg | $750 | 2021-12-16 | Buy |
Properties
Melting point :104-106°C
Boiling point :547.4±50.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO with warming
form :White solid
pka :7.35±0.10(Predicted)
color :White to off-white
Sensitive :Moisture & Light Sensitive
CAS DataBase Reference :304909-07-7
Boiling point :547.4±50.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO with warming
form :White solid
pka :7.35±0.10(Predicted)
color :White to off-white
Sensitive :Moisture & Light Sensitive
CAS DataBase Reference :304909-07-7
Safety Information
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Description
Smoothened (SMO) is a GPCR-like receptor which, with Patched, mediates hedgehog signaling to regulate gene expression through the Gli transcription factors. SANT 1 is a potent inhibitor of hedgehog signaling that acts by directly antagonizing SMO (IC50 = 20 nM). It counteracts SMO activation by the SMO agonist SAG but only partially competes with SAG binding to SMO. SANT 1 targets inactive SMO while it is in the cytoplasm, before it relocates to the primary cilium and is activated. Through antagonism of SMO, SANT 1 represses Gli-mediated transcription in a variety of cell types.More related product prices
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