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BML-259

CAS No.
267654-00-2
Chemical Name:
BML-259
Synonyms
BML-259;CAY10554;N-(5-Isopropylthiazol-2-yl)-2-phenylacetamide;Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]-;2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide;BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent kinase,Alzheimer's
CBNumber:
CB12450947
Molecular Formula:
C14H16N2OS
Molecular Weight:
260.35
MDL Number:
MFCD09802287
MOL File:
267654-00-2.mol
Last updated:2023-09-04 15:51:00

BML-259 Properties

Melting point 150-152℃
storage temp. RT
solubility Soluble in DMSO (up to 25 mg/ml).
form White solid.
color white
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a

BML-259 price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SRP0704 BML-259 recombinant 267654-00-2 25mg $341 2024-03-01 Buy
Alfa Aesar J67143 BML-259, 98% 267654-00-2 5mg $139 2023-06-20 Buy
Cayman Chemical 10010301 CAY10554 ≥95% 267654-00-2 5mg $64 2024-03-01 Buy
Cayman Chemical 10010301 CAY10554 ≥95% 267654-00-2 10mg $119 2024-03-01 Buy
Cayman Chemical 10010301 CAY10554 ≥95% 267654-00-2 25mg $280 2024-03-01 Buy
Product number Packaging Price Buy
SRP0704 25mg $341 Buy
J67143 5mg $139 Buy
10010301 5mg $64 Buy
10010301 10mg $119 Buy
10010301 25mg $280 Buy

BML-259 Chemical Properties,Uses,Production

Description

BML-259 (267654-00-2) is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM) and Cdk2 (IC50 = 98nM).1

Definition

ChEBI: 2-phenyl-N-(5-propan-2-yl-2-thiazolyl)acetamide is a member of acetamides.

References

1) Helal et al. (2004) Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease; Bioorg. Med. Chem. Lett. 14 5521

BML-259 Preparation Products And Raw materials

Raw materials

Preparation Products

BML-259 Suppliers

Global( 42)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
BOC Sciences 16314854226 info@bocsci.com United States 9923 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11217 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 999 58
Zhengzhou convergence chemical co., LTD 0371-0371-55153829 18003835034 2853979819@qq.com China 9717 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62163 58
InvivoChem 13549236410 sales@invivochem.cn China 6753 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24648 58

BML-259 Spectrum

BML-259 CAY10554 2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]- BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent kinase,Alzheimer's N-(5-Isopropylthiazol-2-yl)-2-phenylacetamide 267654-00-2