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BML-259

BML-259 Structure
BML-259 structure
CAS No.
267654-00-2
Chemical Name:
BML-259
Synonyms
BML-259;CAY10554;N-(5-Isopropylthiazol-2-yl)-2-phenylacetamide;Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]-;2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide;BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent kinase,Alzheimer's
CBNumber:
CB12450947
Molecular Formula:
C14H16N2OS
Molecular Weight:
260.35
MDL Number:
MFCD09802287
MOL File:
267654-00-2.mol
Last updated:2023-09-04 15:51:00
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BML-259 Properties

Melting point 150-152℃
storage temp. RT
solubility Soluble in DMSO (up to 25 mg/ml).
form White solid.
color white
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a

BML-259 price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SRP0704 BML-259 recombinant 267654-00-2 25mg $341 2024-03-01 Buy
Alfa Aesar J67143 BML-259, 98% 267654-00-2 5mg $139 2023-06-20 Buy
Cayman Chemical 10010301 CAY10554 ≥95% 267654-00-2 5mg $64 2024-03-01 Buy
Cayman Chemical 10010301 CAY10554 ≥95% 267654-00-2 10mg $119 2024-03-01 Buy
Cayman Chemical 10010301 CAY10554 ≥95% 267654-00-2 25mg $280 2024-03-01 Buy
Product number Packaging Price Buy
SRP0704 25mg $341 Buy
J67143 5mg $139 Buy
10010301 5mg $64 Buy
10010301 10mg $119 Buy
10010301 25mg $280 Buy

BML-259 Chemical Properties,Uses,Production

Description

BML-259 (267654-00-2) is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM) and Cdk2 (IC50 = 98nM).1

Definition

ChEBI: 2-phenyl-N-(5-propan-2-yl-2-thiazolyl)acetamide is a member of acetamides.

References

1) Helal et al. (2004) Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease; Bioorg. Med. Chem. Lett. 14 5521

BML-259 Preparation Products And Raw materials

Raw materials

Preparation Products

BML-259 Suppliers

Global( 42)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
BOC Sciences 16314854226 info@bocsci.com United States 9923 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 999 58
Zhengzhou convergence chemical co., LTD 0371-0371-55153829 18003835034 2853979819@qq.com China 9733 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62075 58
InvivoChem 13549236410 sales@invivochem.cn China 6753 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24644 58
Supplier Advantage
Aladdin Scientific 		58
BOC Sciences 65
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 58
Zhengzhou convergence chemical co., LTD 58
Bide Pharmatech Ltd. 58
InvivoChem 58
TargetMol Chemicals Inc. 58

BML-259 Spectrum

BML-259(267654-00-2)1HNMR

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BML-259 CAY10554 2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]- BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent kinase,Alzheimer's N-(5-Isopropylthiazol-2-yl)-2-phenylacetamide 267654-00-2