Sodium danshensu
- CAS No.
- 67920-52-9
- Chemical Name:
- Sodium danshensu
- Synonyms
- NSC122009;NCI-C02120;NSC 122009;NSC-122009;dium danshensu;Sodium danshensu;DANSHENSU SODIUM (RG);Salvianic acid A sodium;(±)-DanShenSu sodium sal;Salvia natriuretic peptide
- CBNumber:
- CB91117913
- Molecular Formula:
- C9H11NaO5
- Molecular Weight:
- 222.17
- MDL Number:
- MFCD07781415
- MOL File:
- 67920-52-9.mol
- MSDS File:
- SDS
Sodium danshensu price More Price(29)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 27222 | Danshensu (sodium salt) | 67920-52-9 | 25mg | $79 | 2024-03-01 | Buy |
Cayman Chemical | 27222 | Danshensu (sodium salt) | 67920-52-9 | 100mg | $264 | 2024-03-01 | Buy |
Cayman Chemical | 27222 | Danshensu (sodium salt) | 67920-52-9 | 10mg | $34 | 2024-03-01 | Buy |
Cayman Chemical | 27222 | Danshensu (sodium salt) | 67920-52-9 | 50mg | $141 | 2024-03-01 | Buy |
Usbiological | 300987 | Sodium Danshensu | 67920-52-9 | 20mg | $280 | 2021-12-16 | Buy |
Sodium danshensu Chemical Properties,Uses,Production
Description
Danshensu is a salvianolic acid and the major component of S. miltiorrhiza (Danshen) and has diverse biological activities. It reduces expression of the autophagy-associated proteins p62, LC3-II, and Beclin-1 and the apoptosis-related proteins Bax and caspase-3, prevents cardiomyocyte damage, and increases heart rate, coronary flow (CF), and left ventricular developed pressure (LVDP) in an isolated rat heart model of ischemia and reperfusion injury. Danshensu (60 mg/kg per day) reduces infarct size and improves left ventricular function in a rat model of myocardial infarction. It enhances radiation-induced tumor cell death in a Lewis lung carcinoma mouse xenograft model. Danshensu also decreases infarct volume, neuronal apoptosis, production of TNF-α, IL-1β, and IL-6, and superoxide dismutase (SOD) and glutathione peroxidase (GPx) activity in a rat model of cerebral ischemia and reperfusion injury.
Chemical Properties
White to light brown powder
Uses
Sodium Danshensu is exhibits protective effects on the excitotoxicity of monosodium glutamate in the late stage of pregnancy on developing mouse fetal brain.
in vivo
Salvianic acid A (3 or 10 mg/kg, p.o., once daily for 6 weeks) suppresses inflammatory reactions and inhibits oxidative stress in atherosclerosis (AS) rats induced by a high-fat diet, showing protective effects against atherosclerosis[5].
Animal Model: | Atherosclerosis (AS) model induced by a high-fat diet in Sprague-Dawley rats (180-220 g)[4] |
Dosage: | 3 or 10 mg/kg |
Administration: | Oral gavage (p.o.), once daily for 6 weeks |
Result: | Inhibited atherosclerotic lesion progression and reduced aortic lipid deposition by 58.2% and 72.8% in high-fat diet-induced AS rats. Improved lipid profiles by lowering triglyceri/brdes, total cholesterol, and LDL cholesterol while significantly increasing HDL cholesterol in AS rats. Enhanced antioxidant enzyme activity, upregulated the Nrf2/HO-1 pathway, and reduced the expression of p47phox and p22phox. |
target
Calcium Channel | Potassium Channel | Akt | GSK-3 | Bcl-2/Bax | PI3K
Sodium danshensu Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29857 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 | sale02@cqherb.com | CHINA | 376 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
View Lastest Price from Sodium danshensu manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-04-30 | Danshensu sodium salt
67920-52-9
|
US $45.00-85.00 / mg | 97.04% | 10g | TargetMol Chemicals Inc. | ||
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2023-02-24 | Sodium Danshensu
67920-52-9
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
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2023-02-24 | Sodium Danshensu
67920-52-9
|
US $0.00 / mg | 5mg | Analytical Standard | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- Danshensu sodium salt
67920-52-9
- US $45.00-85.00 / mg
- 97.04%
- TargetMol Chemicals Inc.
-
- Sodium Danshensu
67920-52-9
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- Sodium Danshensu
67920-52-9
- US $0.00 / mg
- Analytical Standard
- Shanghai Standard Technology Co., Ltd.