Carisoprodol
- CAS No.
- 78-44-4
- Chemical Name:
- Carisoprodol
- Synonyms
- RELA;CARISOPRODO;Carbamic acid, (1-methylethyl)-, 2-[[(aminocarbonyl)oxy]methyl]-2-methylpentyl ester;NFKB3;Mioril;Sanoma;cb8019;Flexal;Apesan;Arusal
- CBNumber:
- CB0215440
- Molecular Formula:
- C12H24N2O4
- Molecular Weight:
- 260.33
- MOL File:
- 78-44-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/24 15:44:31
| Melting point | 92-92°C |
|---|---|
| Boiling point | 403.59°C (rough estimate) |
| Density | 1.1035 (rough estimate) |
| refractive index | 1.4560 (estimate) |
| storage temp. | 2-8°C |
| solubility | Very slightly soluble in water, freely soluble in acetone, in alcohol and in methylene chloride. |
| form | Solid |
| pka | pKa 4.2 (Uncertain) |
| color | White to Off-White |
| Water Solubility | <0.1 g/100 mL at 19.5 ºC |
| BCS Class | 2/4 |
| CAS DataBase Reference | 78-44-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Carisoprodol(78-44-4) |
| EPA Substance Registry System | Carisoprodol (78-44-4) |
Carisoprodol price More Price(2)
Carisoprodol Chemical Properties,Uses,Production
Description
Carisoprodol (Item No. 30778) is an analytical reference standard categorized as a skeletal muscle relaxant. It also has sedative properties. Carisoprodol is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.
Chemical Properties
White Solid
Uses
Muscle relaxant (skeletal)
Carisoprodol has an onset of action of ca. 30min and a duration of 4–6h. It is administered orally. Presumably, it acts by inhibiting interneuronal activity in the spinal cord and the brainstem reticular formation. Clinically effective doses are accompanied by drowsiness or dizziness; its mechanism may involve sedation.Its CNS depressant effects are additive with those of ethanol and other psychotropic agents. Carisoprodol has a low potential for drug dependence.
Preparation
Carisoprodol is Prepared by reaction of 2-methyl-2-propyl-1,3-pro-panediol with phosgene and ammonium hydroxide, then with isopropyl isocyanate.
Definition
ChEBI: A carbamate ester that is the mono-N-isopropyl derivative of meprobamate (which is a significant metabolite). Carisoprodol interrupts neuronal communication within the reticular formation and spinal cord, resulting in sedation and alter tion in pain perception. It is used as a muscle relaxant in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm.
General Description
Carisoprodol, N-isopropyl-2-methyl-2-propyl-1,3-propanediol dicarbamate, 2-methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate(Soma), is the mono-N-isopropyl–substituted relative ofmeprobamate. The structure is given in the discussion ofmeprobamate. It is indicated in acute skeletomuscular conditionscharacterized by pain, stiffness, and spasm. As canbe expected, a major side effect of the drug is drowsiness.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Carisoprodol is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.
Health Hazard
SYMPTOMS: The most common symptoms of exposure to Carisoprodol are drowsiness and hives. Other symptoms may include nausea, vomiting, epigastric distress, vertigo, ataxia, tremors, agitation, irritability, headache, insomnia, fainting, hiccups, visual disturbances, asthma, fever, hypotension, excitement and paralysis.
Fire Hazard
Flash point data for Carisoprodol are not available, but Carisoprodol it probably combustible.
Carisoprodol Preparation Products And Raw materials
Raw materials
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