FCCP
- CAS No.
- 370-86-5
- Chemical Name:
- FCCP
- Synonyms
- FCCP;FCCCP;p-CF3O-CCP;Carbonyl Cyanide para Trifluoromethoxyphe;4-(TRIFLUOROMETHOXY)PHENYLAZOMALONONITRILE;CARBONOYLCYANID-4-TRIFLUORMETHOXYPHENYL-HYDRAZON;Trifluoromethoxy carbonylcyanide phenylhydrazone;MESOXALONITRILE 4-TRIFLUOROMETHOXYPHENYLHYDRAZONE;Carbonylcyanide-p-trifluoromethoxuphenylhydrazone;CARBONYL CYANIDE 4-TRIFLUOROMETHOXYPHENYLHYDRAZONE
- CBNumber:
- CB0252618
- Molecular Formula:
- C10H5F3N4O
- Molecular Weight:
- 254.17
- MOL File:
- 370-86-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/13 17:03:25
| Melting point | 174-175 °C (dec.)(lit.) |
|---|---|
| Boiling point | 293.3±50.0 °C(Predicted) |
| Density | 1.34±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | acetone: 20 mg/mL, clear, very deep greenish yellow |
| form | powder |
| pka | 5.91±0.10(Predicted) |
| color | yellow |
| BRN | 664446 |
| Stability | Stable for 2 years from date of purchase as supplied. Protect from exposure to moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months. |
| CAS DataBase Reference | 370-86-5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314-H317-H413 | |||||||||
| Precautionary statements | P260-P273-P280-P301+P312-P303+P361+P353-P305+P351+P338 | |||||||||
| Hazard Codes | T,Xi | |||||||||
| Risk Statements | 25-43 | |||||||||
| Safety Statements | 36/37-45 | |||||||||
| RIDADR | UN 2811 6.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | FG5775000 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 2928009090 | |||||||||
| NFPA 704 |
|
FCCP price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C2920 | Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone ≥98% (TLC), powder | 370-86-5 | 10MG | ₹18099.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C2920 | Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone ≥98% (TLC), powder | 370-86-5 | 50MG | ₹59418.43 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C3463 | Carbonyl Cyanide 4-(Trifluoromethoxy)phenylhydrazone min. 95.0 % | 370-86-5 | 10MG | ₹3500 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C3463 | Carbonyl Cyanide 4-(Trifluoromethoxy)phenylhydrazone min. 95.0 % | 370-86-5 | 50MG | ₹6300 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C3463 | Carbonyl Cyanide 4-(Trifluoromethoxy)phenylhydrazone min. 95.0 % | 370-86-5 | 250MG | ₹9800 | 2022-05-26 | Buy |
FCCP Chemical Properties,Uses,Production
Uses
FCCP is a potent uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP synthesis by transporting protons across cell membranes. At 40 μM, FCCP induces complete depolymerization of microtubules by increasing intracellular pH via the disruption of the mitochondrial H+ gradient and by decreasing the stability of microtubules by impairing the binding of microtubule-associated proteins.[Cayman Chemical]
Definition
ChEBI: A hydrazone that is hydrazonomalononitrile in which one of the hydrazine hydrogens is substituted by a p-trifluoromethoxyphenyl group.
Biological Activity
A very potent uncoupler of oxidative phosphorylation in mitochondria.
FCCP Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 148)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | China | 3957 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29889 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | China | 3136 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
370-86-5(FCCP)Related Search:
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COENZYME Q2
7-CHLORO-5-(2-CHLOROPHENYL)-1,5-DIHYDRO-4,1-BENZOTHIAZEPIN-2(3H)-ONE
CITRININ
BA, 3NH4
CARBONYL CYANIDE 3-CHLOROPHENYLHYDRAZONE
DECYLUBIQUINONE
Malononitrile
FCCP
4-(Trifluoromethoxy)aniline
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((4-(trifluoromethoxy)phenyl)hydrazono)-propanedinitril
MESOXALONITRILE 4-TRIFLUOROMETHOXYPHENYLHYDRAZONE
2-[2-[4-(TRIFLUOROMETHOXY)PHENYL]HYDRAZONO]MALONONITRILE
4-(TRIFLUOROMETHOXY)PHENYLAZOMALONONITRILE
mesoxalonitrile,(p-(trifluoromethoxy)phenyl)hydrazone
[[4-(trifluoromethoxy)phenyl]hydrazono]malononitrile
CARBONYL CYANIDE P-(TRIFLUOROMETHOXY)PHE NYLHYDRAZO
CARBONOYLCYANID-4-TRIFLUORMETHOXYPHENYL-HYDRAZON
FCCP, Mesoxalonitrile 4-trifluoromethoxyphenylhydrazone
2-[4-(Trifluoromethoxy)phenyl]hydrazonopropanedinitrile
p-CF3O-CCP
Carbonylcyanide-p-trifluoromethoxuphenylhydrazone
{2-[4-(Trifluoromethoxy)phenyl]hydrazinylidene}propane-1,3-dinitrile, 4-[2-(Dicyanomethylidene)hydrazino]-alpha,alpha,alpha-trifluoroanisole
Trifluoromethoxy carbonylcyanide phenylhydrazone
2-[2-[4-(Trifluoromethoxy)phenyl]hydrazinylidene]propanedinitrile
FCCCP
CARBONYL CYANIDE 4-TRIFLUOROMETHOXYPHENYLHYDRAZONE
CARBONYL CYANIDE P-(TRI-FLUOROMETHOXY)PHENYL-HYDRAZONE
CARBONYL CYANIDE P-TRIFLUOROMETHYL PHENYLHYDRAZONE
FCCP
Propanedinitrile, 2-[2-[4-(trifluoromethoxy)phenyl]hydrazinylidene]-
Propanedinitrile, [[4-(trifluoromethoxy)phenyl]hydrazono]-
2-[[4-(trifluoromethoxy)phenyl]hydrazinylidene]propanedinitrile
(4-(Trifluoromethoxy)phenyl)hydrazonopropanedinitrile
Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazon
Carbonyl Cyanide para Trifluoromethoxyphe
Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone|||Trifluoromethoxy carbonylcyanide phenylhydrazone
370-86-5
C10H5F3N4O
CF3OC6H4NHNCCN2
Enzyme Inhibitors
Enzymes, Inhibitors, and Substrates
Enzyme Inhibitors by Type
Organic Covalent Modifiers
Biochemicals and Reagents
BioChemical
Signalling
Caspases/Apoptosis