ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Hydrazone >CARBONYL CYANIDE 3-CHLOROPHENYLHYDRAZONE
CARBONYL CYANIDE 3-CHLOROPHENYLHYDRAZONE
- CAS No.
- 555-60-2
- Chemical Name:
- CARBONYL CYANIDE 3-CHLOROPHENYLHYDRAZONE
- Synonyms
- CCCP;Carbonyl Cyanide;(3-CHLOROPHENYL)HYDRAZONOMALONONITRILE;MESOXALONITRILE 3-CHLOROPHENYLHYDRAZONE;CCCP;CCCPH;M-CL-CCP;m-Cl-CCP (CCCP);BUTTPARK 91\04-41;TIMTEC-BB SBB003506;CCCP apoptosis inducer;3-chlorophenylhydrazone
- CBNumber:
- CB0421559
- Molecular Formula:
- C9H5ClN4
- Molecular Weight:
- 204.62
- MOL File:
- 555-60-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 170-175 °C (dec.) |
|---|---|
| Boiling point | 333.84°C (rough estimate) |
| Density | 1.3807 (rough estimate) |
| refractive index | 1.6110 (estimate) |
| storage temp. | -20°C |
| solubility | methanol: 10 mg/mL, clear, very deep yellow |
| form | powder |
| pka | 6.00±0.10(Predicted) |
| color | yellow to orange |
| Water Solubility | Insoluble in water. Soluble in DMSO (5 mg/ml), ethanol (1 mg/ml) and methanol (10 mg/ml). |
| BRN | 1842102 |
| Exposure limits | NIOSH: IDLH 25 mg/m3 |
| InChIKey | UGTJLJZQQFGTJD-UHFFFAOYSA-N |
| CAS DataBase Reference | 555-60-2(CAS DataBase Reference) |
| EPA Substance Registry System | Propanedinitrile, [(3-chlorophenyl)hydrazono]- (555-60-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311+H331-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P310-P302+P352+P312-P304+P340+P311-P305+P351+P338 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 23/24/25-36/37/38 | |||||||||
| Safety Statements | 26-36/37-45 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | FG5600000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29280090 | |||||||||
| NFPA 704 |
|
CARBONYL CYANIDE 3-CHLOROPHENYLHYDRAZONE price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C2759 | Carbonyl cyanide 3-chlorophenylhydrazone ≥97% (TLC), powder | 555-60-2 | 100MG | ₹3897 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C2759 | Carbonyl cyanide 3-chlorophenylhydrazone ≥97% (TLC), powder | 555-60-2 | 250MG | ₹8584.23 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C2759 | Carbonyl cyanide 3-chlorophenylhydrazone ≥97% (TLC), powder | 555-60-2 | 1G | ₹19192.73 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 215911 | Carbonyl Cyanide m-Chlorophenylhydrazone - CAS 555-60-2 - Calbiochem Protonophore. Uncoupling agent for oxidative phosphorylation that inhibits mitochondrial function. Approximately 100 times more effective than 2,4-din | 555-60-2 | 250MG | ₹15820 | 2022-06-14 | Buy |
| ALFA India | ALF-L06932-ME | Carbonyl cyanide 3-chlorophenylhydrazone, 98% | 555-60-2 | 500mg | ₹5754 | 2022-05-26 | Buy |
CARBONYL CYANIDE 3-CHLOROPHENYLHYDRAZONE Chemical Properties,Uses,Production
Description
CCCP is a protonophore mitochondrial uncoupler that increases membrane permeability to protons, leading to a disruption in the mitochondrial membrane potential. It inhibits mitochondrial respiration and ATPase activity when used at concentrations of 110 and 35 nM, respectively. CCCP inhibits activation of stimulation of interferon genes (STING), decreasing the expression of downstream STING targets, including IFN-β, TBK1, and IRF3 when used at a concentration of 50 μM in RAW 264.7 cells. It induces mitochondrial fission in a manner dependent on the GTPase Drp1. CCCP (4 mg/kg) increases body temperature as well as left ventricular systolic and diastolic dimensions and decreases fractional shortening in rats. It also increases myocardial glucose and fatty acid uptake in rats.
Chemical Properties
yellow to orange-brown crystalline powder
Uses
Carbonyl cyanide 3-chlorophenylhydrazone is a widely used uncoupler of oxidative phosphorylation.
Biological Activity
Widely used uncoupler of oxidative phosphorylation.
CARBONYL CYANIDE 3-CHLOROPHENYLHYDRAZONE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 138)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21667 | 55 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29889 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | China | 4088 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | China | 4128 | 58 | Inquiry |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | China | 3136 | 58 | Inquiry |
555-60-2(CARBONYL CYANIDE 3-CHLOROPHENYLHYDRAZONE)Related Search:
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CCCP
(3-CHLOROPHENYL)HYDRAZONOMALONONITRILE;MESOXALONITRILE 3-CHLOROPHENYLHYDRAZONE;CCCP
CCCP，Mesoxalonitrile 3-chlorophenylhydrazone
555-60-2
C9H5ClN4
C9H5CIN4
ClC6H4NHNCCN2
Organic Covalent Modifiers
Enzyme Inhibitors
Enzymes, Inhibitors, and Substrates
Enzyme Inhibitors by Type
BioChemical
Biochemicals and Reagents
Caspases/Apoptosis