Potassium sorbate
- CAS No.
- 24634-61-5
- Chemical Name:
- Potassium sorbate
- Synonyms
- (E,E)-hexadienoic acid, potassium salt;e202;suanjia;FEMA 2921;trans-trans-So;Potassium otassium sorbate;potassium sorbat;Potassium sorbate;POTASSIUM SARBATE
- CBNumber:
- CB0294184
- Molecular Formula:
- C6H7KO2
- Molecular Weight:
- 150.22
- MOL File:
- 24634-61-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/4/11 21:28:41
| Melting point | 270 °C |
|---|---|
| Density | 1,361 g/cm3 |
| vapor pressure | <1 Pa (20 °C) |
| FEMA | 2921 | POTASSIUM SORBATE |
| storage temp. | 2-8°C |
| solubility | H2O: 1 M at 20 °C, clear, colorless to faintly yellow |
| pka | 4.69[at 20 ℃] |
| form | Powder |
| color | White to light cream |
| PH | 7.8 (H2O, 20.1℃) |
| Odor | Odorless |
| PH Range | 8 - 11 at 580 g/l at 20 °C |
| Water Solubility | 58.2 g/100 mL (20 ºC) |
| Merck | 14,7671 |
| BRN | 5357554 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | CHHHXKFHOYLYRE-STWYSWDKSA-M |
| LogP | -1.72 at 20℃ |
| CAS DataBase Reference | 24634-61-5(CAS DataBase Reference) |
| EPA Substance Registry System | Potassium sorbate (24634-61-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P305+P351+P338 | |||||||||
| Hazard Codes | Xi,C,T,F | |||||||||
| Risk Statements | 36/37/38-35-22 | |||||||||
| Safety Statements | 26-36-45-36/37/39 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | WG2170000 | |||||||||
| Autoignition Temperature | >150 °C | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 2916 19 95 | |||||||||
| Toxicity | LD50 orally in Rabbit: 3800 mg/kg | |||||||||
| NFPA 704 |
|
Potassium sorbate price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 85520 | Potassium sorbate purum p.a., ≥99.0% (NT) | 24634-61-5 | 50G | ₹1407.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 85520 | Potassium sorbate purum p.a., ≥99.0% (NT) | 24634-61-5 | 250G | ₹3160.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1278 | Potassium sorbate Pharmaceutical Secondary Standard; Certified Reference Material | 24634-61-5 | 1G | ₹7371.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 85520 | Potassium sorbate purum p.a., ≥99.0% (NT) | 24634-61-5 | 1KG | ₹7404.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 47848 | Potassium Sorbate analytical standard | 24634-61-5 | 1000MG | ₹2684.6 | 2022-06-14 | Buy |
Potassium sorbate Chemical Properties,Uses,Production
Description
Potassium sorbate is a white crystalline powder. It is a potassium salt of sorbic acid.It was originally discovered in the 1850’s, and was derived from the Mountain Ash Tree. Today, potassium sorbate is synthetically created.Potassium sorbate is a good food preservatives, fully degradable, similar to fatty acids found naturally in foods. It is used to slow the growth of molds and yeasts in foods. It is commonly found in margarine, wines, cheeses, yogurts, soft drinks, and baked goods. Potassium sorbate has been used has a food preservative for many years. There have been extensive long-term tests that have confirmed its safety and it is on the Center for Science in the Public Interest list of safe additives.
Chemical Properties
Potassium sorbate occurs as a white crystalline powder with a faint, characteristic odor.
Physical properties
Colorless or white crystalline solid; density 1.36 g/cm3; decomposes at 270°C; soluble in water, 58 g/100 g solution; moderately soluble in alcohol.
Uses
Sorbic acid and its potassium salt is commonly employed as food preservative in wide range of foodstuffs, such as cheese, pickles, sauces and wines.
Potassium sorbate is a food grade preservative generally regarded as safe (GRAS) worldwide. It is the inactive salt of sorbic acid. It readily dissolves in water where it converts to sorbic acid, its active form, at a low pH. Sorbic acid is very pH dependent. While it shows some activity up to pH 6 (about 6%), it is most active at pH 4.4 (70%). At pH 5.0 it is 37% active. As sorbic acid, it is considered to be active against mold, fair against yeast and poor against most bacteria. Sorbic acid is an unsaturated fatty acid and as such is subject to oxidation (use of an antioxidant like Mixed Tocopherols T50 is recommended). It is also sensitive to UV light and may turn yellow in solution. Gluconolactone is reported to stabilize potassium sorbate against discoloration and darkening in aqueous solutions and may be useful in stabilizing sorbic acid in the water phase of a product.
Preparation
Potassium sorbate is prepared by reacting potassium hydroxide with sorbic acid, followed by evaporation and crystallization:CH3CH=CHCH=CHCOOH + KOH →CH3CH=CHCH=CHCOOK + H2O.
Production Methods
Potassium sorbate is prepared from sorbic acid and potassium hydroxide.
Definition
ChEBI: A potassium salt having sorbate as the counterion.
General Description
Sorbates have been reported to be less toxic than benzoate and have been classified as “Generally Recognized as Safe” (GRAS) additives by the U.S. Food and Drug Administration (FDA).Sorbic acid is metabolised to mainly to carbon dioxide. While the minor amounts are converted to trans,trans-muconic acid (ttMA), which is excreted unchanged into the urine. Urinary ttMA is a biomarker for the occupational and environmental exposure to benzene. Ability of trans,trans-2,4-Hexadienoic acid potassium salt (Sorbic acid potassium salt, Potassium sorbate) to induce chromosome aberrations, sister chromatid exchanges (SCE) and gene mutations in cultured Chinese hamster V79 cells has been examined.Potassium sorbate is reported to be less genotoxic than the sodium salt analog.
Pharmaceutical Applications
Potassium sorbate is an antimicrobial preservative, with antibacterial
and antifungal properties used in pharmaceuticals, foods, enteral
preparations, and cosmetics. Generally, it is used at concentrations
of 0.1–0.2% in oral and topical formulations, especially those
containing nonionic surfactants. Potassium sorbate has been used to
enhance the ocular bioavailability of timolol.
Potassium sorbate is used in approximately twice as many
pharmaceutical formulations as is sorbic acid owing to its greater solubility and stability in water. Like sorbic acid, potassium sorbate
has minimal antibacterial properties in formulations above pH 6.
Toxicology
Potassium sorbate is a skin, eye and respiratory irritant. Although some research implies it has a long term safety record, in vitro studies have shown that it is both genotoxic and mutagenic to human blood cells. Potassium sorbate is found to be toxic to human DNA in peripheral blood lymphocytes (type of white blood cells), and hence found that it negatively affects immunity. It is often used with ascorbic acid and iron salts as they increase its effectiveness but this tends to form mutagenic compounds that damage DNA molecules.
Potassium sorbate exhibits low toxicity with LD50 (rat, oral) of 4.92 g / kg, similar to that of table salt . Typical usage rates of potassium sorbate are 0.025 % to 0.1 % (see sorbic acid), which in a 100 g serving yields intake of 25 mg to 100 mg. Acceptable daily intakes for human is 12.5 mg / kg, or 875 mg daily for an average adult (70 kg), according to FAO/World Health Organization Expert Committee on Food Additives.
Safety
Potassium sorbate is used as an antimicrobial preservative in oral
and topical pharmaceutical formulations and is generally regarded
as a relatively nontoxic material. However, some adverse reactions
to potassium sorbate have been reported, including irritant skin
reactions which may be of the allergic, hypersensitive type. There
have been no reports of adverse systemic reactions following oral
consumption of potassium sorbate.
The WHO has set an estimated total acceptable daily intake for
sorbic acid, calcium sorbate, potassium sorbate, and sodium
sorbate expressed as sorbic acid at up to 25 mg/kg body-weight.
(mouse, IP): 1.3 g/kg
(rat, oral): 4.92 g/kg
See also Sorbic Acid.
storage
Potassium sorbate is more stable in aqueous solution than sorbic
acid; aqueous solutions may be sterilized by autoclaving.
The bulk material should be stored in a well-closed container,
protected from light, at a temperature not exceeding 40°C.
Incompatibilities
Some loss of antimicrobial activity occurs in the presence of nonionic surfactants and some plastics.
Regulatory Status
GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (nasal sprays; oral capsules, solutions, suspensions, syrups, tablets; topical creams and lotions). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Potassium sorbate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ARRAKIS INDUSTRIES LLP | +91 74995 32711 | Maharashtra, India | 1353 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Scientific OEM | +91-22- 2343 7546 / 2341 3094 | New Delhi, India | 1994 | 38 | Inquiry |
| ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1679 | 43 | Inquiry |
| National Drugs & Chemicals | 91 2228933489 | New Delhi, India | 11 | 62 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4315 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6157 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
| LOBA CHEMIE PVT.LTD. | 91-22-6663 6699 | Mumbai, India | 3075 | 58 | Inquiry |
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