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3-Aminobenzamide

3-Aminobenzamide Structure
CAS No.
3544-24-9
Chemical Name:
3-Aminobenzamide
Synonyms
3-AB;3-ABA;INO-1001;PARP-IN-1;3-AB, 3-ABA;M-AMINOBENZAMIDE;3-AMINOBENZAMIDE;3-amino-benzamid;m-amino-benzamid;META-AMINOBENZAMIDE
CBNumber:
CB0681621
Molecular Formula:
C7H8N2O
Molecular Weight:
136.15
MOL File:
3544-24-9.mol
Modify Date:
2024/8/17 21:30:02

3-Aminobenzamide Properties

Melting point 115-116 °C (lit.)
Boiling point 250.42°C (rough estimate)
Density 1.1778 (rough estimate)
refractive index 1.5769 (estimate)
storage temp. room temp
solubility ethanol: 50 mg/mL, clear, faintly yellow
form powder
pka 16.26±0.50(Predicted)
color white to off-white
Water Solubility Soluble in dimethylformamide (~30 mg/ml), dimethyl sulfoxide (~30 mg/ml), phosphate buffered saline (pH7.2) (~2 mg/ml), water (25 mg/ml), and ethanol (25 mg/ml).
Sensitive Light Sensitive
BRN 2802373
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
LogP -0.330
CAS DataBase Reference 3544-24-9(CAS DataBase Reference)
NIST Chemistry Reference 3-NH2-C6H4CONH2(3544-24-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P301+P312+P330-P304+P340+P312-P305+P351+P338-P337+P313-P261-P280a-P304+P340-P405-P501a-P264-P270-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
RIDADR  3077
WGK Germany  3
RTECS  CU8992000
HS Code  29242990
NFPA 704
1
2 0

3-Aminobenzamide price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A0788 3-Aminobenzamide ≥99% (TLC) 3544-24-9 100MG ₹7530 2022-06-14 Buy
Sigma-Aldrich(India) A0788 3-Aminobenzamide ≥99% (TLC) 3544-24-9 250MG ₹14440 2022-06-14 Buy
Sigma-Aldrich(India) A0788 3-Aminobenzamide ≥99% (TLC) 3544-24-9 1G ₹37940 2022-06-14 Buy
Sigma-Aldrich(India) A0788 3-Aminobenzamide ≥99% (TLC) 3544-24-9 5G ₹74180 2022-06-14 Buy
Sigma-Aldrich(India) 165350 PARP Inhibitor I, 3-ABA - CAS 3544-24-9 - Calbiochem The PARP Inhibitor I, 3-ABA, also referenced under CAS 3544-24-9, controls the biological activity of PARP. This small molecule/inhibitor is primarily 3544-24-9 100MG ₹5880 2022-06-14 Buy
Product number Packaging Price Buy
A0788 100MG ₹7530 Buy
A0788 250MG ₹14440 Buy
A0788 1G ₹37940 Buy
A0788 5G ₹74180 Buy
165350 100MG ₹5880 Buy

3-Aminobenzamide Chemical Properties,Uses,Production

Description

The poly(ADP-ribose) polymerases (PARPs) comprise a family of enzymes which post-translationally modify proteins by poly(ADP-ribosyl)ation. Since some PARPs are activated by DNA strand breaks, PARP signaling has roles in DNA repair, apoptosis, inflammation, and other cellular responses. 3-amino Benzamide is an inhibitor of PARPs (Ki = 1.8 μM). Through its effects on PARPs, 3-amino benzamide causes telomere shortening and stimulates angiogenesis. It has PARP-mediated actions in such diverse diseases as atherosclerosis, neurogenesis, and cancer.

Chemical Properties

beige powder

Uses

3-Aminobenzamide is used as an endogenous poly-ADP-ribosyltransferase inhibitor. Through its effects on PARPs, 3-amino benzamide causes telomere shortening and stimulates angiogenesis. It displays neuroprotective, anti-necrotic effects.

Definition

ChEBI: A substituted aniline that is benzamide in which one of the meta- hydrogens is replaced by an amino group.

3-Aminobenzamide Preparation Products And Raw materials

Global( 255)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Syn Finechem Laboratories Pvt Ltd +91-4023095094 +91-9848230784 Telangana, India 194 58 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
NSC Organics 08069013898Ext 371 Hyderabad, India 166 58 Inquiry
Basr Fine Chemicals Private Limited 08068442227Ext 547 Hyderabad, India 632 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-81138252 +86-18789408387 China 3957 58 Inquiry
Hebei Mojin Biotechnology Co., Ltd +86 13288715578 +8613288715578 China 12447 58 Inquiry
Hebei Chuanghai Biotechnology Co,.LTD +86-13131129325 China 5867 58 Inquiry
m-Amino Benzamide 3-Amino Benzamide 3-AB, 3-ABA 3-Aminobenzamide,3-AB, 3-ABA INO-1001 3-AMinobenzaMide, 98% 1GR 3-AMinobenzaMide, 98% 5GR Benzamide, 3-amino- (9CI) 3-Aminobenzamide,98% META-AMINOBENZAMIDE M-AMINOBENZAMIDE 3-ABA 3-AMINOBENZAMIDE PARP Inhibitor I, 3-ABA 3-amino-benzamid Benzamide, 3-amino- Benzamide, m-amino- m-amino-benzamid 3-AB 3-Aminobenzamide > PARP-IN-1 PARP-IN-1 (3-aminobenzamide PARP Inhibitor I, 3-ABA - CAS 3544-24-9 - Calbiochem 3-AMINOBENZAMIDE;INO1001;INO 1001 INO-1001 (3-Aminobenzamide Aminobenzamide, 3- - AB, 3- | ABA, 3- 3544-24-9 PARP PARP Regulators Organic Building Blocks Building Blocks Apoptosis and Cell Cycle BioChemical Amides Cell Biology Carbonyl Compounds Cell Signaling and Neuroscience A-AM Amides Bioactive Small Molecules AMIDE Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts Inhibitors Inhibitor Building Blocks Carbonyl Compounds Cell Biology Chemical Synthesis Organic Building Blocks