Luminol
- CAS No.
- 521-31-3
- Chemical Name:
- Luminol
- Synonyms
- LUMINOL;3-Aminophthalhydrazide;5-Amino-2,3-dihydro-1,4-phthalazinedione; Luminol; 3-Aminophthalhydrazide (Luminol);Luminol and sodium salt;5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE;uminoL;Ruminos;NSC 5064;LuMinol 97%;Luminol ,98%;LuMinol
- CBNumber:
- CB1275687
- Molecular Formula:
- C8H7N3O2
- Molecular Weight:
- 177.16
- MOL File:
- 521-31-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/10/28 16:48:35
| Melting point | >300 °C (lit.) |
|---|---|
| Boiling point | 309.07°C (rough estimate) |
| Density | 1.3393 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | Insoluble in water, soluble in dimethyl sulfoxide. |
| form | Powder |
| pka | (Calcd.) 10.50 ± 0.20;;0.58 ± 0.20(at 25℃) |
| color | Dark green to dark blue-purple |
| PH Range | NonH uorescence (6.0) to blue H uorescence (7.0) |
| Water Solubility | <0.1 g/100 mL at 19 ºC |
| λmax | 425nm |
| Merck | 14,5600 |
| BRN | 383929 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, strong bases, strong reducing agents. Emits light on reaction with oxidizers. |
| Major Application | Night vision devices, identification of product forgeries, determination of nitride in food, analytical chemistry, pharmaceuticals, iodine in biological materials, evaluating phagocytes, detecting tumors, DNA, biosensors, assay of fungi, bacteria, yeasts, assay of lipase activity |
| InChIKey | HWYHZTIRURJOHG-UHFFFAOYSA-N |
| LogP | -0.245 (est) |
| CAS DataBase Reference | 521-31-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 3-Aminophthalhydrazide(521-31-3) |
| EPA Substance Registry System | Luminol (521-31-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H302-H335 | |||||||||
| Precautionary statements | P280h-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22-20/21/22 | |||||||||
| Safety Statements | 26-36/37-37/39-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TH8890060 | |||||||||
| F | 10-23 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29339990 | |||||||||
| NFPA 704 |
|
Luminol price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A8511 | Luminol ≥97% (HPLC) | 521-31-3 | 5G | ₹3734.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A8511 | Luminol ≥97% (HPLC) | 521-31-3 | 25G | ₹14819.43 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.20071 | 5-Amino-2,3-dihydrophthalazine-1,4-dione for synthesis | 521-31-3 | 1G | ₹2940.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 123072 | Luminol 97% | 521-31-3 | 2.5G | ₹3897 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.20071 | 5-Amino-2,3-dihydrophthalazine-1,4-dione for synthesis | 521-31-3 | 10G | ₹6230 | 2022-06-14 | Buy |
Luminol Chemical Properties,Uses,Production
Chemical Properties
yellow crystals or beige powder
Uses
Luminol is used in the detection of copper, iron, peroxides and cyanides. It exhibits chemiluminescence and utilized to measure opsonic and phagocytic function. It acts as a biological sensor and involved in the detection of polymorphonuclear leukocytes response in a patient with a myeloperoxidase deficiency. Further, it is used as a forensic test for blood.
General Description
Yellow crystals or light beige powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Oxidation of 3-Aminophthalhydrazide is accompanied by a striking emission of light. . .
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition 3-Aminophthalhydrazide emits toxic fumes.
Fire Hazard
Flash point data for 3-Aminophthalhydrazide are not available, but 3-Aminophthalhydrazide is probably combustible.
Synthesis
The synthesis of Luminol is as follows: To a reaction tube, add 140 mg of 3-nitrophthalhydrazide and 1.0 mL of 3 M sodium hydroxide solution. Stir with a rod, and to the resulting deep brown-red solution add 0.6 g of sodium hydrosulfite dihydrate (Na2S2O4 · 2 H2O, MW 210.2). Wash down the sides of the tube with a small amount of water. Heat to a gentle boil and keep the tube hot for 5 minutes. During this time some product may begin to crystallize. Add 0.4 mL of acetic acid, cool the tube in cold water, and stir. Collect the light-yellow product Luminol by suction filtration.
Purification Methods
Dissolve luminol in KOH solution, treat with Norit (charcoal), filter and precipitate it with conc HCl. [Hardy et al. Talanta 24 297 1977.] Store it in the dark in an inert atmosphere, because its structure changes during its luminescence. It has been recrystallised from 0.1M KOH [Merenyi et al. J Am Chem Soc 108 77716 1986]. [Beilstein 25 II 389, 25 III/IV 4192.]
Luminol Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ACME SUJAN CHEMICALS | +91 7588647937 | Maharashtra, India | 90 | 58 | Inquiry |
| Earthchem Laboratories P Ltd | +91-9923536956 +91-9923536947 | Maharashtra, India | 59 | 58 | Inquiry |
| Pallav Chemicals And Solvents Pvt Ltd | +91-9136093115 +91-9136093115 | Maharashtra, India | 1364 | 58 | Inquiry |
| ARRAKIS INDUSTRIES LLP | +91 74995 32711 | Maharashtra, India | 1353 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6202 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6700 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5870 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| ACME SUJAN CHEMICALS | 58 |
| Earthchem Laboratories P Ltd | 58 |
| Pallav Chemicals And Solvents Pvt Ltd | 58 |
| ARRAKIS INDUSTRIES LLP | 58 |
| OCEAN TRADING CORPORATION | 58 |
| CHEMSWORTH | 30 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
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