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2-Pyridylethylamine

2-Pyridylethylamine Structure
CAS No.
2706-56-1
Chemical Name:
2-Pyridylethylamine
Synonyms
lilly04432;2-PYRIDYLETHYLAMINE;RARECHEM AL BW 0258;Demethylbetahistine;2-aminoethylpyridine;2-Pyridineethanamine;2-pyridineethylamine;Pyridine-2-ethanamine;alpha-Pyridylethylamine;2-(2-PYRIDYL)ETHYLAMINE
CBNumber:
CB1137534
Molecular Formula:
C7H10N2
Molecular Weight:
122.17
MOL File:
2706-56-1.mol
MSDS File:
SDS
Modify Date:
2024/5/10 16:01:40

2-Pyridylethylamine Properties

Melting point 198-200 °C(Solv: ethanol (64-17-5))
Boiling point 92-93 °C12 mm Hg(lit.)
Density 1.021 g/mL at 25 °C(lit.)
refractive index n20/D 1.536(lit.)
Flash point 213 °F
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form Liquid
pka pK1: 4.24(+2);pK2: 9.78(+1) (25°C,μ=0.05)
color Clear colorless to yellow
Specific Gravity 1.021
Water Solubility Soluble in water (partly), and most common polar solvent. Insoluble in non-polar solvents, and oils.
Sensitive Air Sensitive
BRN 111208
CAS DataBase Reference 2706-56-1(CAS DataBase Reference)
NIST Chemistry Reference 2-Pyridineethanamine(2706-56-1)
EPA Substance Registry System 2-Pyridineethanamine (2706-56-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38-34
Safety Statements  26-36-45-36/37/39
RIDADR  2735
WGK Germany  3
10-34
TSCA  Yes
HazardClass  8
PackingGroup  III
HS Code  29333990
NFPA 704
1
3 0

2-Pyridylethylamine price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A55306 2-(2-Pyridyl)ethylamine 95% 2706-56-1 1G ₹3301.63 2022-06-14 Buy
Sigma-Aldrich(India) A55306 2-(2-Pyridyl)ethylamine 95% 2706-56-1 10G ₹11604.4 2022-06-14 Buy
Sigma-Aldrich(India) A55306 2-(2-Pyridyl)ethylamine 95% 2706-56-1 50G ₹72029.55 2022-06-14 Buy
TCI Chemicals (India) A1999 2-(2-Aminoethyl)pyridine min. 98.0 % 2706-56-1 5G ₹4300 2022-05-26 Buy
TCI Chemicals (India) A1999 2-(2-Aminoethyl)pyridine min. 98.0 % 2706-56-1 25G ₹15300 2022-05-26 Buy
Product number Packaging Price Buy
A55306 1G ₹3301.63 Buy
A55306 10G ₹11604.4 Buy
A55306 50G ₹72029.55 Buy
A1999 5G ₹4300 Buy
A1999 25G ₹15300 Buy

2-Pyridylethylamine Chemical Properties,Uses,Production

Chemical Properties

clear colorless to yellow liquid

Uses

2-(2-Aminoethyl)pyridine is used as active pharmaceutical ingredients.

Definition

ChEBI: An aminoalkylpyridine that is pyridine substituted by a ethanamino group at position 2.

Biological Activity

Low doses of histamine or H1R agonist 2-pyridylethylamine (2-PEA) into the knee-joint were found to decrease formalin-induced articular nociception in rats. The pharmacological blockade and neurotoxic ablation of cells expressing neuropeptide Y1 receptor (Y1R) in the spinal cord were able to prevent the antinociceptive effect produced by the intra-articular administration of the histamine H1 receptor (H1R) agonist, 2-pyridylethilamine (2-PEA), in the formalin-induced articular incapacitation in rats[1].

References

[1] Eduardo Souza-Silva. “Intra-articular injection of 2-pyridylethylamine produces spinal NPY-mediated antinociception in the formalin-induced rat knee-joint pain model.” Brain Research 1735 (2020): Article 146757.

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RARECHEM AL BW 0258 2-PYRIDYLETHYLAMINE 2-Pyridineethanamine 2-(PYRIDIN-2-YL)ETHANAMINE 2-PYRIDIN-2-YL-ETHYLAMINE 2-aminoethylpyridine 2-(2-AMINOETHYL)PYRIDINE 2-(2-PYRIDYL)ETHYLAMINE 2-(2-Pyridinyl)ethanamine 2-(beta-Aminoethyl)pyridine alpha-Pyridylethylamine Demethylbetahistine lilly04432 Pyridine, 2-(2-aminoethyl)- 2-pyridineethylamine 2-(2-PYRIDYL)ETHYLAMINE 95+% 2-Pyridin-2-ylethanamin 2-(2-Aminoethyl)pyridine ,98% 2-(2-Pyridyl)ethanamine Pyridine-2-ethanamine 2-(2-Aminoethyl)pyridine,95% 2-(2-Pyridyl)ethylaMine 95% .alpha.-(2-Aminoethyl)pyridine 2-(2-AMinoethyl)pyridine, 95% 10GR 2-(2-AMinoethyl)pyridine, 95% 1GR (2-pyridin-2-ylethyl)amine(SALTDATA: FREE) 2-Pyridylethylamine ISO 9001:2015 REACH 2-(2-Aminoethyl)pyridine > 2-(2-Aminoethyl)pyridine 98% Betahistine Impurity 11 2-Pyridineethanamine (9CI, ACI) 2706-56-1 Building Blocks C7 and C8 Heterocyclic Building Blocks Pyridines Pyridine