2-(2-Bromoethyl)-1,3-dioxolane
- CAS No.
- 18742-02-4
- Chemical Name:
- 2-(2-Bromoethyl)-1,3-dioxolane
- Synonyms
- Bromoethyldioxolane;2KG;)-1,3-dioxoL;2-(2-BromoethyL;2-(2-Bromoethyl)-1,3;2-bromo-2-(2-ethyl)dioxolane;2-(2-Bromoethyl)-1,3-dioxola;2-(2-BROMOETHYL)-1,3-DIOXOLANE;3-Bromopropanal ethylene acetal;1,3-Dioxolane, 2-(2-bromoethyl)-
- CBNumber:
- CB1156942
- Molecular Formula:
- C5H9BrO2
- Molecular Weight:
- 181.03
- MOL File:
- 18742-02-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/13 17:03:25
| Boiling point | 68-70 °C8 mm Hg(lit.) |
|---|---|
| Density | 1.542 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 149 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
| form | clear liquid |
| color | brownish-yellow |
| Specific Gravity | 1.541.542 |
| Water Solubility | immiscible |
| Sensitive | Light Sensitive |
| BRN | 103516 |
| InChIKey | GGZQLTVZPOGLCC-UHFFFAOYSA-N |
| CAS DataBase Reference | 18742-02-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-(2-Bromoethyl)-1,3-dioxolane(18742-02-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335 | |||||||||
| Precautionary statements | P301+P310+P330-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| RIDADR | UN 2810 6.1/PG 3 | |||||||||
| WGK Germany | 2 | |||||||||
| F | 8-9 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
2-(2-Bromoethyl)-1,3-dioxolane price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 230995 | 2-(2-Bromoethyl)-1,3-dioxolane 96% | 18742-02-4 | 10G | ₹2284.08 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 230995 | 2-(2-Bromoethyl)-1,3-dioxolane 96% | 18742-02-4 | 50G | ₹7674.93 | 2022-06-14 | Buy |
| TCI Chemicals (India) | B1132 | 2-(2-Bromoethyl)-1,3-dioxolane min. 90.0 % | 18742-02-4 | 25G | ₹5200 | 2022-05-26 | Buy |
| ALFA India | ALF-A11441-18 | 2-(2-Bromoethyl)-1,3-dioxolane, 95%, stab. with silver | 18742-02-4 | 50g | ₹12295 | 2022-05-26 | Buy |
| TCI Chemicals (India) | B1132 | 2-(2-Bromoethyl)-1,3-dioxolane min. 90.0 % | 18742-02-4 | 100G | ₹16700 | 2022-05-26 | Buy |
2-(2-Bromoethyl)-1,3-dioxolane Chemical Properties,Uses,Production
Chemical Properties
Clear colorless to yellow or brown liquid
Uses
2-(2-Bromoethyl)-1,3-dioxolane is used as a pharmaceutical intermediate, dioxolanes, acetals, ketals, building blocks, chemical synthesis, organic building blocks and oxygen compounds. 1,1-(Ethylenedioxy)-3-bromopropane is used in the synthesis of EGFR inhibitors. Also used in the synthesis of orally active agents of cancer and cell proliferation with quinoline substructures. It is also used as flavouring agent.
General Description
Copper-catalyzed borylation of 2-(2-bromoethyl)-1,3-dioxolane with bis(pinacolato)diboron followed by treatment with potassium bifluoride affords the key organotrifluoroborate reagent.
Purification Methods
Dissolve it in pentane, wash with 5% aqueous NaHCO3, dry (Na2SO4), and evaporate. Distil the residue. [NMR: Büchi & Wüest J Org Chem 34 1122 1969, Kriesat & Gisvold J Pharm Sci 60 1250 1971, Beilstein 19/1 V 69.]
2-(2-Bromoethyl)-1,3-dioxolane Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 318)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| Stereokem Pvt Ltd | +91-4029706929 +91-9394224843 | Telangana, India | 350 | 58 | Inquiry |
| M M Kemicals | +91-7032683572 +91-9989927761 | Telangana, India | 38 | 58 | Inquiry |
| Pragmetis Pharmaserves LLP | +919601601452 | Gujarat, India | 15 | 58 | Inquiry |
| Erevna Pharma Private Limited | +91-9962143988 +91-9884394900 | Telangana, India | 46 | 58 | Inquiry |
| Enzal Chemicals (India) Limited | 91-22-56926473 -78 | New Delhi, India | 120 | 50 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| Stereokem Pvt Ltd | 58 |
| M M Kemicals | 58 |
| Pragmetis Pharmaserves LLP | 58 |
| Erevna Pharma Private Limited | 58 |
| Enzal Chemicals (India) Limited | 50 |
| CHEMSWORTH | 30 |
| OCEAN TRADING CORPORATION | 58 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
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2-(2-Bromoethyl)-1,3-dioxolane >
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Bromoethyldioxolane
18742-02-4
Organic Building Blocks
Oxygen Compounds
Acetals/Ketals/Ortho Esters
Dioxanes & Dioxolanes
Dioxolanes
Building Blocks
Acetals/Ketals/Ortho Esters
Building Blocks
Chemical Synthesis
Organic Building Blocks
Oxygen Compounds
Pyridines ,Heterocyclic Acids
Miscellaneous
Dioxanes & Dioxolanes
Dioxolanes