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ChemicalBook > Product Catalog >Biochemical Engineering >Saccharides >Monosaccharide >D-Mannose

D-Mannose

D-Mannose Structure
CAS No.
3458-28-4
Chemical Name:
D-Mannose
Synonyms
Aldohexos;D-MANNOPYRANOSE;D-MANOSE;D-MAN;CARUBINOSE;D-MannMtol;α-D-mannose;d-[1,2,3-13C3]Mannose;DL-allo-2,3,4,5,6-Pentahydroxy-hexanal;SEMINOSE
CBNumber:
CB1175305
Molecular Formula:
C6H12O6
Molecular Weight:
180.16
MOL File:
3458-28-4.mol
Modify Date:
2024/6/19 22:55:17
Request For Quotation

D-Mannose Properties

Melting point 133-140 °C(lit.)
alpha 14 º (589nm, c=10, H2O)
Boiling point 232.96°C (rough estimate)
Density 1,539 g/cm3
refractive index 1.5730 (estimate)
storage temp. room temp
solubility H2O: 50 mg/mL
form powder
pka 12.08(at 25℃)
color White
optical activity [α]20/D +13.8±0.5°, 24 hr, c = 10% in H2O
Water Solubility 2480 g/L (17 ºC)
Sensitive Hygroscopic
λmax λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1
Merck 14,5747
BRN 1564373
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey WQZGKKKJIJFFOK-ATJJXCEKSA-N
LogP -2.71 at 25℃
CAS DataBase Reference 3458-28-4(CAS DataBase Reference)
NIST Chemistry Reference D-Mannose(3458-28-4)
EPA Substance Registry System D-Mannose (3458-28-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
F  3
TSCA  Yes
HS Code  29400010
NFPA 704
1 0

D-Mannose price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) M8574 D-(+)-Mannose synthetic, ≥99% 3458-28-4 25G ₹4578.98 2022-06-14 Buy
Sigma-Aldrich(India) M8574 D-(+)-Mannose synthetic, ≥99% 3458-28-4 100G ₹11550.28 2022-06-14 Buy
Sigma-Aldrich(India) PHR2044 Mannose Pharmaceutical Secondary Standard; Certified Reference Material 3458-28-4 1G ₹12914.23 2022-06-14 Buy
Sigma-Aldrich(India) M8574 D-(+)-Mannose synthetic, ≥99% 3458-28-4 500G ₹42693.8 2022-06-14 Buy
Sigma-Aldrich(India) M6020 D-(+)-Mannose powder, BioReagent, suitable for cell culture 3458-28-4 25G ₹6928 2022-06-14 Buy
Product number Packaging Price Buy
M8574 25G ₹4578.98 Buy
M8574 100G ₹11550.28 Buy
PHR2044 1G ₹12914.23 Buy
M8574 500G ₹42693.8 Buy
M6020 25G ₹6928 Buy

D-Mannose Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Uses

D-Mannose is a carbohydrate that is important in the glycosylation of molecules in a variety of cellular processes. It is involved in N and O glycosylation of bovine why protein products, used in inf ant formulas. It is also responsible for the O-glycosylation of the T helper cell-derived cytokine interlukin-17A, an important cell-signaling molecule.

Application

D-mannose is a simple sugar structurally related to glucose. It is absorbed slowly from the gastrointestinal tract, and then a large proportion of it is excreted into the urine.
D-(+)-Mannose has been used:
as a reference standard in monosaccharide analysis and quantification from sea squirts Ascidiella aspersa
as a medium component for the selection of P898012 sorgum seeds transfected with Agrobacterium
in segmented filamentous bacterium (SFB) medium supplement for culturing human cell lines
Mannose is an aldohexose carbohydrate. It is isomer of glucose with varying C2 position configuration. Majority of mannose is synthesised from its epimer glucose. It is part of the glycans present in endoplasmic reticulum (ER)/Golgi.

Definition

ChEBI: D-Mannopyranose having alpha-configuration at the anomeric centre.

General Description

Mannose is a monosaccharide.

Side effects

D-mannose appears to be generally well tolerated in people. You should be cautious about using D-mannose if you are pregnant or breastfeeding, because there has not been enough study on its safety in these circumstances. Side effects of D-mannose may include: bloating and loose stools. D-mannose supplements should be used with caution if you have diabetes. It may make it harder to control your blood sugar. High doses of D-mannose may cause kidney damage.

Purification Methods

Crystallise -D(+)-mannose repeatedly from EtOH, aqueous 80% EtOH, AcOH or MeOH/propan-2-ol and then dry it in vacuo over P2O5 at 60o. [For 1H NMR and equilibr

D-Mannose Preparation Products And Raw materials

Raw materials

D-Mannitol METHYL B-D-MANNOPYRANOSIDE ISOPROPYLATE METHYL-ALPHA-D-MANNOPYRANOSIDE

Preparation Products

5-Hydroxymethylfurfural Methyl levulinate BENZYL ALPHA-D-MANNOPYRANOSIDE 1-5-ANHYDRO-D-MANNITOL CRYSTALLINE AMYL LACTATE
δ-D-Mannonolactone GLYCOLALDEHYDE 2,4-dihydroxy-Butanoic acid D(-)-Fructose Pyridoxine
Nsc39317
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D-Mannose Suppliers

Global( 647)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
S D Fine Chem Limited +91-9323715856 +91-9323715856 Maharashtra, India 368 58 Inquiry
AKASH PHARMA EXPORTS +91-9388123451 +91-9846039283 Kerela, India 470 58 Inquiry
ALPHA CHEMIKA +91-22-22061123 +91-22-66382501 Mumbai, India 1681 43 Inquiry
Scientific OEM +91-22- 2343 7546 / 2341 3094 New Delhi, India 1996 38 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Maas Pharma Chemicals +91-9958666224 Delhi, India 1607 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5873 58 Inquiry
Supplier Advantage
S D Fine Chem Limited 58
AKASH PHARMA EXPORTS 58
ALPHA CHEMIKA 43
Scientific OEM 38
CHEMSWORTH 30
TCI Chemicals (India) Pvt. Ltd. 58
CLEARSYNTH LABS LTD. 58
Maas Pharma Chemicals 58
A.J Chemicals 58
Otto Chemie Pvt. Ltd. 58

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D-Mannose Spectrum

D-Mannose(3458-28-4)1HNMRD-Mannose(3458-28-4)IR1D-Mannose(3458-28-4)Raman

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d-[1-12C]Mannose (13C depleted at C1) d-[1-13C:1-2H]Mannose d-[1-18O]Mannose d-[2,3,4,5,6-13C5]Mannose d-[3,4-13C2]Mannose d-[UL-12C6]Mannose (13C depleted) d-[UL-13C6:UL-2H7]Mannose d-[UL-2H7]Mannose >=95% (RadiocheMical Purity, HPLC) YM MEDIUM BROTH E D-Mannose(Plant Extract) D-(+)-MANNOSE D-MANNOSE MANNOSE, D-(+)- D-MANNOSE extrapure AR D-MANNOSERESEARCH GRADE D-(+)-Mannose,D-Mannopyranose D-(+)-Mannose 99.5% D-(+)-Maose Mannose (300 mg) NSC 26247 (2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal SEMINOSE d-mannos D(+)-MANNOSE SIGMAULTRA D(+)-MANNOSE MIXED ANOMERS*CELL CULTURE TESTED D-MANNOSE, 99%, MIXTURE OF ANOMERS D-(+)-MANNOSE 99.5+% ULTRA PURE D-(+)-MANNOSE 99% CELL CUTLURE REAGENT D-MannoseForBiochemistry99% D (+) MANNOSE FOR BIOCHEMISTRY D-MANNOSE FOR BIOCHEMISTRY 99% D-(+)-Mannose,99% D-MANNOSE,REAGENT (3S,4S,5R,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol MALTOSE, D-(RG) MANNOSE, D-(+)-(RG) D-(+)-MANNOSE - NATURAL GMO FREE D-Mannose - F D-Mannose - F (from birch) 1,3,4,6-Tetra-O-acetyl-2-O-trifluoromethanesulfonyl-&beta 1,2,3,4,6-Penta-O-acetyl-&alpha 2-O-Benzyl-1,3,4-tri-O-acetyl-&alpha 2-O-(2-Deoxy-2-N-phthalimido-3,4,6-tri-O-acetyl-&beta 1,6,2,3-Di(isopropylidene) &beta 2-O-(2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-&beta -D-glucopyranosyl)-3-O-benzyl-4,6-O-benzylidene-&alpha 3,6-Di-O-(3,4,6-tri-O-acetyl-&beta -D-mannopyranosylethylidyne)-1,2-O-ethylidene-&beta 4-O-Acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-&alpha -D-mannopyranosyl)-1,2|-ethylidene-&beta d mannose E:candyli(at)speedgainpharma(dot)com 99% D-Mannose 4-O-Acetyl-3,6-di-O-(3,4,6-tri-O-acetyl-&beta Benzyl-2-O-(2-Acetamido-2-deoxy-&beta 1,3,4,6-Tetra-O-acetyl-&beta 1,6-Anhydro-2,3-O-(1-isopropylidene)-4-O-(2,3,4,6-tetra-O-acetyl-&alpha 1,6-Anhydro-4-O-(2,3,4,6-tetra-O-acetyl-&alpha