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2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione

2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione Structure
CAS No.
446292-07-5
Chemical Name:
2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione
Synonyms
C21H2IN3Os .;2-Amino-12-picoline;Rivaroxaban Impurity 50;Rivaroxaban interMediate B;Intermediate of Rivaroxaban 4;-2-(2-Hydroxy-3-((4-(3-oxomorpholino);Rivaroxaban Phthalimido Descarbonyl Impurity;2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}pr...;4-[((2R)-Hydroxy-3-phthaliMido)propylaMine]phenyl-3-Morpholinone;2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]-
CBNumber:
CB12468597
Molecular Formula:
C21H21N3O5
Molecular Weight:
395.41
MOL File:
446292-07-5.mol
Modify Date:
2024/6/12 17:09:27
Request For Quotation

2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione Properties

Melting point 208-211°C
Boiling point 734.9±60.0 °C(Predicted)
Density 1.421
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka 13.91±0.20(Predicted)
form Solid
color White to Off-White
Water Solubility 37mg/L at 20℃
LogP 0.6 at 25℃
CAS DataBase Reference 446292-07-5

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501
HS Code  2922498590

2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Rivaroxaban intermediate.

2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione Preparation Products And Raw materials

Raw materials

4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one (S)-(+)-Glycidyl Phthalimide 4-(4-AMINOPHENYL)MORPHOLIN-3-ONE 3-Morpholinone, 4-phenyl- 4-(4-NITROPHENYL)MORPHOLIN-3-ONE
N-(2,3-EPOXYPROPYL)PHTHALIMIDE 2-Anilinoethanol p-Phenylenediamine 1H-Isoindol-1-one, 3-hydroxy- Potassium phthalimide
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Preparation Products

2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione Suppliers

Global( 248)Suppliers
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SRIGEN LIFE SCIENCES PVT LTD +919866542802 Hyderabad, India 60 58 Inquiry
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Supplier Advantage
SRIGEN LIFE SCIENCES PVT LTD 58
Prash Intermediates 58
Acute Research 58
Cubane Pharmaceuticals LLP 58
Aspen Biopharma Labs Pvt Ltd 58
CHEMAZON LABORATORIES 58
Opulant Pharmaceuticals Pvt Ltd 58
SynZeal Research Pvt Ltd 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Pab Organics Private Limited 58

446292-07-5(2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione)Related Search:

1,2-BenzenedicarboxaMide, N1,N2-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- 2-QuinazolineMethanol, 4-Methyl- Rivaroxaban Impurity 34 (R)-N-Glycidylphthalimide 4,5-DICHLOROTHIOPHENE-2-CARBOXYLIC ACID
2-Thiophenecarboxylic acid 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Rivaroxaban POLYSTYRENE IODOSOACETATE 1,2-Cyclohexanedione
(S)-(+)-Epichlorohydrin 4-(4-NITROPHENYL)MORPHOLIN-3-ONE (S)-(+)-Glycidyl Phthalimide 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl
5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE Ethyl (R)-(-)-4-cyano-3-hydroxybutyate 3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]-
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1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- 4-[((2R)-Hydroxy-3-phthaliMido)propylaMine]phenyl-3-Morpholinone 2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione 2-[(2R)-2-hydroxy-3-{[4-(3-oxoMorpholin-4-yl)phenyl]aMino}p ropyl]-1H-isoindole-1,3(2H)-dione (R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)-amino)propyl)isoindoline-1,3-dione Rivaroxaban interMediate B 2-[(2R)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl]isoindole-1,3-dione Rivaroxaban Phthalimido Descarbonyl Impurity 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- -2-(2-Hydroxy-3-((4-(3-oxomorpholino) Rivaroxaban Impurity 10/4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone Rivaroxaban Impurity 50 H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- R –(2-Hydroxy-3-((4-(3-Oxo morpholino) Phenyl) Amino) Propyl) Isoindoline-1,3-dione 2-Amino-12-picoline 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}pr... TIANFUCHEM--446292-07-5---1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]- C21H2IN3Os . Intermediate of Rivaroxaban 4 446292-07-5 Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Intermediate of Rivaroxaban