(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide
- CAS No.
- 168835-82-3
- Chemical Name:
- (E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide
- Synonyms
- CS-1481;CHEMBL261508;SU1498, >98%;Tyrphostin SU 1498, >98%;(E)-2-CYANO-3-(4-HYDROXY-3;AG-1498;TYRPHOSTIN SU 1498;5-DIISOPROPYLPHENYL)-N-(3-PHENYLPROPYL)ACRYLAMIDE;(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropy;(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide;2-Propenamide, 2-cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-, (2E)-
- CBNumber:
- CB12514856
- Molecular Formula:
- C25H30N2O2
- Molecular Weight:
- 390.52
- MOL File:
- 168835-82-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 17:06:34
| Melting point | 126 °C |
|---|---|
| Boiling point | 590.6±50.0 °C(Predicted) |
| Density | 1.100±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO. |
| pka | 10.30±0.36(Predicted) |
| form | powder |
| color | white to beige |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
| CAS DataBase Reference | 168835-82-3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| HS Code | 2926.90.4801 | |||||||||
| NFPA 704 |
|
(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML1193 | SU1498 ≥98% (HPLC) | 168835-82-3 | 5MG | ₹12188.95 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML1193 | SU1498 ≥98% (HPLC) | 168835-82-3 | 25MG | ₹49091.38 | 2022-06-14 | Buy |
| TCI Chemicals (India) | U0103 | SU 1498 | 168835-82-3 | 5MG | ₹5400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | U0103 | SU 1498 | 168835-82-3 | 25MG | ₹14800 | 2022-05-26 | Buy |
(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide Chemical Properties,Uses,Production
Uses
SU 1498 is an inhibitor of VEGF receptor kinase.
Biochem/physiol Actions
SU1498 is a potent and selective inhibitor of the VEGFR2 receptor kinase, Flk-1 with an IC50 value of 700 nM. SU1498 is a very weak inhibitor of PDGFR-kinase, EGFR-kinase and HER-2 kinase with IC50 values > 50 μM. SU1498 has been used to study the role of VEGFR2 (Flk-1) in a variety of biological activities including angiogenesis, tumor growth inhibition, and stem cell proliferation.
(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 44)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Focus Biomolecules | 855-362-8721 | United States | 1284 | 58 | Inquiry |
| Adamas Reagent, Ltd. | 400-6009262 16621234537 | China | 14113 | 59 | Inquiry |
| BOC Sciences | USA | 0 | 65 | Inquiry | |
| DC Chemicals | 021-58447131 13564518121 | China | 9412 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| ATK CHEMICAL COMPANY LIMITED | 60 |
| InvivoChem | 58 |
| TargetMol Chemicals Inc. | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 58 |
| Aladdin Scientific | 58 |
| Focus Biomolecules | 58 |
| Adamas Reagent, Ltd. | 59 |
| BOC Sciences | 65 |
| DC Chemicals | 58 |
168835-82-3((E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide)Related Search:
(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide
(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropy
SU1498, >98%
Tyrphostin SU 1498, >98%
CS-1481
(E)-2-CYANO-3-(4-HYDROXY-3
5-DIISOPROPYLPHENYL)-N-(3-PHENYLPROPYL)ACRYLAMIDE
CHEMBL261508
SU1498; TYRPHOSTIN SU 1498; CHEMBL261508; (E)-2-CYANO-3-(4-HYDROXY-3;5-DIISOPROPYLPHENYL)-N-(3-PHENYLPROPYL)ACRYLAMIDE
AG-1498;TYRPHOSTIN SU 1498
2-Propenamide, 2-cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-, (2E)-
Vascular endothelial growth factor receptor,Inhibitor,Su-1498,AG1498,AG-1498,Su1498,Tyrphostin SU1498,inhibit,Tyrphostin SU-1498,VEGFR,SU 1498
168835-82-3