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(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide

(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide Structure
  • ₹5400 - ₹49091.38
  • Product name: (E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide
  • CAS: 168835-82-3
  • MF: C25H30N2O2
  • MW: 390.52
  • EINECS:
  • MDL Number:MFCD03453026
  • Synonyms:(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide;(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropy;SU1498, >98%;Tyrphostin SU 1498, >98%;CS-1481;(E)-2-CYANO-3-(4-HYDROXY-3;5-DIISOPROPYLPHENYL)-N-(3-PHENYLPROPYL)ACRYLAMIDE;CHEMBL261508
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerTCI Chemicals (India)
  • Product numberU0103
  • Product descriptionSU 1498
  • Packaging5MG
  • Price₹5400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberU0103
  • Product descriptionSU 1498
  • Packaging25MG
  • Price₹14800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1193
  • Product descriptionSU1498 ≥98% (HPLC)
  • Packaging5MG
  • Price₹12188.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1193
  • Product descriptionSU1498 ≥98% (HPLC)
  • Packaging25MG
  • Price₹49091.38
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) U0103 SU 1498 5MG ₹5400 2022-05-26 Buy
TCI Chemicals (India) U0103 SU 1498 25MG ₹14800 2022-05-26 Buy
Sigma-Aldrich(India) SML1193 SU1498 ≥98% (HPLC) 5MG ₹12188.95 2022-06-14 Buy
Sigma-Aldrich(India) SML1193 SU1498 ≥98% (HPLC) 25MG ₹49091.38 2022-06-14 Buy

Properties

Melting point :126 °C
Boiling point :590.6±50.0 °C(Predicted)
Density :1.100±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO.
pka :10.30±0.36(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
CAS DataBase Reference :168835-82-3

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases. It effectively blocks signaling through VEGFR2 both in vitro and in vivo. SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.

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