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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Tinib Antineoplastic drugs >Sunitinib Malate

Sunitinib Malate

Sunitinib Malate Structure
  • ₹15891.1 - ₹63477.8
  • Product name: Sunitinib Malate
  • CAS: 341031-54-7
  • MF: C26H33FN4O7
  • MW: 532.57
  • EINECS:638-825-9
  • MDL Number:MFCD08282795
  • Synonyms:EZSolution Sunitinib Malate;Malic acid Shu;N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioic acid (1:1) salt;SU 011248;SU112248;Sunitinib Malate(SU 11248);Butanedioic acid, 2;N-(2-(Diethylamino)ethyl)-5-((Z)-(5-fluoro-1
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberPZ0012
  • Product descriptionSunitinib malate ≥98% (HPLC)
  • Packaging5MG
  • Price₹15891.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPZ0012
  • Product descriptionSunitinib malate ≥98% (HPLC)
  • Packaging25MG
  • Price₹63477.8
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PZ0012 Sunitinib malate ≥98% (HPLC) 5MG ₹15891.1 2022-06-14 Buy
Sigma-Aldrich(India) PZ0012 Sunitinib malate ≥98% (HPLC) 25MG ₹63477.8 2022-06-14 Buy

Properties

Melting point :189-191°C
storage temp. :room temp
solubility :DMSO: >10mg/mL
form :powder
color :Orange
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :XGQXULJHBWKUJY-LYIKAWCPSA-N
SMILES :[C@@H](O)(C(=O)O)CC(=O)O.C(/C1NC(C)=C(C(=O)NCCN(CC)CC)C=1C)=C1/C(NC2=CC=C(F)C=C/12)=O |&1:0,r|
CAS DataBase Reference :341031-54-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Sunitinib malate is a small molecule, multi-targeted receptor tyrosine kinase inhibitor. It potently inhibits signaling through PDGFR, VEGFR, KIT, and FLT3. Through these effects, sunitinib malate inhibits both tumor cell growth and angiogenesis, leading to reduced tumor vascularization and cancer cell death. It has been approved by the FDA for the treatment of gastrointestinal stromal tumors and metastatic renal cell carcinoma.

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Jigs Chemical ltd Sris Synthesis Pvt Ltd., Bulat Pharmaceutical Pvt Ltd GLP Pharma Standards Hetero Drugs Limited Shilpa Medicare Limited (SML) Vannsh Life Sciences Pvt Ltd Basil Drugs AND Pharmaceuticals Pvt Ltd Raising Sun Pharma Mac Chem Products (India) Pvt Ltd (Naprod Group)