SU 11274
- ₹13100 - ₹88981.5
- Product name: SU 11274
- CAS: 658084-23-2
- MF: C28H30ClN5O4S
- MW: 568.09
- EINECS:
- MDL Number:MFCD08276928
- Synonyms:PKI-SU11274;N-(3-Chlorophenyl)-N-methyl-3-[[3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl]methylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide;N-(3-Chlorophenyl)-N-methyl-3-[[3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl]methylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide SU11274;SU 11274, >=98%;Met Kinase Inhibitor;(Z)-N-(3-Chlorophenyl)-3-((3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl)methy;(3z)-n-(3-chlorophenyl)-3-({3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1h-pyrrol-2-yl}methylene)-n-methyl-2-oxo-2,3-dihydro-1h-indole-5-sulfonamide;SU 11274,SU 11274
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product number448101
- Product descriptionMet Kinase Inhibitor - CAS 658084-23-2 - Calbiochem The Met Kinase Inhibitor, also referenced under CAS 658084-23-2, controls the biological activity of Met Kinase. This small molecule/inhibitor is prim
- Packaging1MG
- Price₹13100
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS9820
- Product descriptionSU 11274 ≥98% (HPLC), powder
- Packaging25MG
- Price₹88981.5
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 448101 | Met Kinase Inhibitor - CAS 658084-23-2 - Calbiochem The Met Kinase Inhibitor, also referenced under CAS 658084-23-2, controls the biological activity of Met Kinase. This small molecule/inhibitor is prim | 1MG | ₹13100 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | S9820 | SU 11274 ≥98% (HPLC), powder | 25MG | ₹88981.5 | 2022-06-14 | Buy |
Properties
Density :1.401±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 10 mg/mL at 60 °C
pka :11.62±0.20(Predicted)
form :powder
color :orange
InChIKey :FPYJSJDOHRDAMT-KQWNVCNZSA-N
storage temp. :2-8°C
solubility :DMSO: 10 mg/mL at 60 °C
pka :11.62±0.20(Predicted)
form :powder
color :orange
InChIKey :FPYJSJDOHRDAMT-KQWNVCNZSA-N
Safety Information
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Description
MET is a proto-oncogene which encodes the hepatocyte growth factor receptor c-Met. It has normal roles in morphogenesis, migration, apoptosis, and angiogenesis. Dysregulation of c-Met occurs in a many types of cancer. SU11274 is a potent, selective, ATP-competitive inhibitor of c-Met (IC50 = 20 nM). It has much less or no activity against other receptor tyrosine kinases. SU11274 induces apoptosis and cell cycle arrest in transformed BaF3 cells and cancer cell lines.More related product prices
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