1,9-Pyrazoloanthrone
|
- ₹6100 - ₹60295.25
- Product name: 1,9-Pyrazoloanthrone
- CAS: 129-56-6
- MF: C14H8N2O
- MW: 220.23
- EINECS:204-955-6
- MDL Number:MFCD00022289
- Synonyms:Dibenzo[cd,g]indazol-6(2H)-one;Nsc75890;Wln: T C6665 1A p iv omnj;SP600125 >99%;JNK Inhibitor II, 1,9-Pyrazoloanthrone;c.i.70300 ;SAPK INHIBITOR I;SAPK INHIBITOR II
6 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 10MG
- 25MG
- 50MG
- ManufacturerTCI Chemicals (India)
- Product numberA2548
- Product descriptionAnthra[1,9-cd]pyrazol-6(2H)-one
- Packaging25MG
- Price₹6100
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number420119
- Product descriptionJNK Inhibitor II - CAS 129-56-6 - Calbiochem JNK Inhibitor II. SP600125, CAS 129-56-6, is a potent, cell-permeable, selective, and ATP competitive inhibitor of c-Jun N-terminal kinase (JNK; IC??
- Packaging5MG
- Price₹9909.99
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS5567
- Product descriptionSP600125 ≥98% (HPLC)
- Packaging10MG
- Price₹15100.88
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number420119
- Product descriptionJNK Inhibitor II - CAS 129-56-6 - Calbiochem JNK Inhibitor II. SP600125, CAS 129-56-6, is a potent, cell-permeable, selective, and ATP competitive inhibitor of c-Jun N-terminal kinase (JNK; IC??
- Packaging25MG
- Price₹29890
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number420119
- Product descriptionJNK Inhibitor II - CAS 129-56-6 - Calbiochem JNK Inhibitor II. SP600125, CAS 129-56-6, is a potent, cell-permeable, selective, and ATP competitive inhibitor of c-Jun N-terminal kinase (JNK; IC??
- Packaging50MG
- Price₹37350
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS5567
- Product descriptionSP600125 ≥98% (HPLC)
- Packaging50MG
- Price₹60295.25
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | A2548 | Anthra[1,9-cd]pyrazol-6(2H)-one | 25MG | ₹6100 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | 420119 | JNK Inhibitor II - CAS 129-56-6 - Calbiochem JNK Inhibitor II. SP600125, CAS 129-56-6, is a potent, cell-permeable, selective, and ATP competitive inhibitor of c-Jun N-terminal kinase (JNK; IC?? | 5MG | ₹9909.99 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S5567 | SP600125 ≥98% (HPLC) | 10MG | ₹15100.88 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 420119 | JNK Inhibitor II - CAS 129-56-6 - Calbiochem JNK Inhibitor II. SP600125, CAS 129-56-6, is a potent, cell-permeable, selective, and ATP competitive inhibitor of c-Jun N-terminal kinase (JNK; IC?? | 25MG | ₹29890 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 420119 | JNK Inhibitor II - CAS 129-56-6 - Calbiochem JNK Inhibitor II. SP600125, CAS 129-56-6, is a potent, cell-permeable, selective, and ATP competitive inhibitor of c-Jun N-terminal kinase (JNK; IC?? | 50MG | ₹37350 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S5567 | SP600125 ≥98% (HPLC) | 50MG | ₹60295.25 | 2022-06-14 | Buy |
Properties
Melting point :281~282℃
Boiling point :361.16°C (rough estimate)
Density :1.1702 (rough estimate)
refractive index :1.5910 (estimate)
storage temp. :2-8°C
solubility :H2O: insoluble
form :Yellowish orange solid
pka :11.75±0.20(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
InChIKey :ACPOUJIDANTYHO-UHFFFAOYSA-N
CAS DataBase Reference :129-56-6(CAS DataBase Reference)
EPA Substance Registry System :Anthra[1,9-cd]pyrazol-6(2H)-one (129-56-6)
Boiling point :361.16°C (rough estimate)
Density :1.1702 (rough estimate)
refractive index :1.5910 (estimate)
storage temp. :2-8°C
solubility :H2O: insoluble
form :Yellowish orange solid
pka :11.75±0.20(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
InChIKey :ACPOUJIDANTYHO-UHFFFAOYSA-N
CAS DataBase Reference :129-56-6(CAS DataBase Reference)
EPA Substance Registry System :Anthra[1,9-cd]pyrazol-6(2H)-one (129-56-6)
Safety Information
| Symbol(GHS): |
|
||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||||||||||||||||
| Hazard statements: |
|
||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
SP 600125 is a potent and reversible inhibitor of JNK1-3 with an IC50 value of 0.11 ?M.1 It is cell-permeable and dose-dependently inhibits c-Jun phosphorylation in cells, blocking the expression of COX-2 and TNF-α in monocytes and IL-10, TNF-α, and IFN-γ in T-cells. SP 600125 also prevents apoptosis in many cell types, including B-cells, and inhibits autophagy in HeLa cells. Competitively and reversibly inhibits JNK1, 2 and 3 (IC50 = 40 - 90 nM) with negligible activity at ERK2, p38β and a range of enzymes (IC50 > 10 ?M). Active in vivo. Shown to have reduced selectivity over other protein kinases under certain conditions. Protects renal tubular epithelial cells against ischemia/reperfusion-induced apoptosis. Prevents BMP9-induced osteogenic differentiation of MSCs.Related product price
- Pyraclostrobine
₹6776.45 - Mefenpyr-diethyl
₹7200-14600 - 89-25-8
₹909-45529.95
Suppliers and manufacturers
Otto Chemie Pvt. Ltd.
TCI Chemicals (India) Pvt. Ltd.
A.J Chemicals
ATK CHEMICAL COMPANY LIMITED
CONIER CHEM AND PHARMA LIMITED
