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SU 4312

SU 4312 Structure
  • ₹13834.35
  • Product name: SU 4312
  • CAS: 5812-07-7
  • MF: C17H16N2O
  • MW: 264.32
  • EINECS:
  • MDL Number:MFCD00118147
  • Synonyms:3-[[(4-DIMETHYLAMINO)PHENYL]METHYLENE]-1,3-DIHYDRO-2H-INDOL-2-ONE;3-(4-DIMETHYLAMINOBENZYLIDENYL)-2-INDOLINONE;3-[[(4-Dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one, E/Z mixture;NSC 86429;SU 4312;2H-Indol-2-one, 3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro;(Z)-3-(4-(DIMETHYLAMINO)BENZYLIDENE)INDOLIN-2-ONE;SU4312(NSC86429)
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberS8567
  • Product descriptionSU 4312 ≥98% (HPLC)
  • Packaging5MG
  • Price₹13834.35
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) S8567 SU 4312 ≥98% (HPLC) 5MG ₹13834.35 2022-06-14 Buy

Properties

Melting point :225-232 °C
Boiling point :497.1±45.0 °C(Predicted)
Density :1.219±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 30 mg/mL
form :Orange solid.
pka :12.89±0.20(Predicted)
color :orange
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SU 4312 is a selective and potent vascular endothelial cell growth factor receptor (VEGFR) inhibitor. Inhibition of Flk-1 (VEGFR-2) in neonatal rodent models of stroke, has been shown to limit endothelial cell proliferation and promote cell death. SU 4312 is an inhibitor of Flg, Flt-1 and PDGFR-β.

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