3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester

3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Structure
CAS No.
1014691-61-2
Chemical Name:
3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester
Synonyms
CS-738;GSK 0660;GSK-0660, >=98%;GSK-0660 (GSK0660);GSK0660 >=98% (HPLC);GSK-0660;GSK 0660;GSK0660;4-Chloro-3-iodo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine;METHYL 3-[(4-ANILINO-2-METHOXYPHENYL)SULFAMOYL]THIOPHENE-2-CARBOXYLATE;methyl 3-{[2-methoxy-4-(phenylamino)phenyl]sulfamoyl}thiophene-2-carboxylate;Methyl 3-(N-(2-Methoxy-4-(phenylaMino)phenyl)sulfaMoyl)thiophene-2-carboxylate
CBNumber:
CB12518768
Molecular Formula:
C19H18N2O5S2
Molecular Weight:
418.49
MOL File:
1014691-61-2.mol
MSDS File:
SDS
Modify Date:
2023/9/20 16:43:00

3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Properties

Boiling point 608.1±65.0 °C(Predicted)
Density 1.413±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble10mg/mL, clear
form powder
pka 8.51±0.50(Predicted)
color white to beige
InChIKey NDFKBGWLUHKMFY-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

WGK Germany  2

3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) G5797 GSK0660 ≥98% (HPLC) 1014691-61-2 5MG ₹14440 2022-06-14 Buy
Product number Packaging Price Buy
G5797 5MG ₹14440 Buy

3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Chemical Properties,Uses,Production

Uses

GSK0660 has been used to study the effects of bezafibrate (BZA) on hypertrophy.

General Description

GSK0660 has antiangiogenic property in oxygen-induced retinopathy. It also regulates tumor necrosis factor-α (TNFα)-induced inflammation in human retinal microvascular endothelial cells (HRMECs).

Biochem/physiol Actions

GSK0660 is a potent PPARβ/δ antagonist with a pIC50 of 6.8 (160 nM). GSK0660 is nearly inactive on PPARα and PPARγ with IC50s greater than 10 μM.

3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Preparation Products And Raw materials

Raw materials

Preparation Products

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3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Spectrum

1014691-61-2(3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester)Related Search:

GSK-0660, >=98% 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester GSK 0660 Methyl 3-(N-(2-Methoxy-4-(phenylaMino)phenyl)sulfaMoyl)thiophene-2-carboxylate 2-Thiophenecarboxylic acid, 3-[[[2-methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-, methyl ester 4-Chloro-3-iodo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine METHYL 3-[(4-ANILINO-2-METHOXYPHENYL)SULFAMOYL]THIOPHENE-2-CARBOXYLATE 3-(2-Methoxy-4-phenylamino-phenylsulfamoyl)-thiophene-2-carboxylic acid methyl ester CS-738 GSK-0660 (GSK0660) GSK-0660;GSK 0660;GSK0660 GSK0660 >=98% (HPLC) methyl 3-{[2-methoxy-4-(phenylamino)phenyl]sulfamoyl}thiophene-2-carboxylate 1014691-61-2 Inhibitors