Selonsertib

CAS No.: 1448428-04-3

Chemical Name:: Selonsertib

Synonyms: GS 4997;CS-2217;GS-4497;Selonsertib;GS-4997;ASK-1;GS4997;GS 4997;GS4997 SELONSERTIB;Selonsertib GS-4997;Selonsertib free base.;Selonsertib (Synonyms: GS-4997)

CBNumber:: CB03122039

Molecular Formula:: C24H24FN7O

Molecular Weight:: 445.49

MOL File:: 1448428-04-3.mol

Modify Date:: 2023/6/8 9:02:48

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Selonsertib Properties

Melting point	>180°C (dec.)
Density	1.39±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in DMSO (>25 mg/ml)
form	solid
pka	11.21±0.70(Predicted)
color	White
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference	1448428-04-3

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS08

Signal word

Warning

Hazard statements

H373

Precautionary statements

P260-P314-P501

NFPA 704

	0
2		0

Selonsertib Chemical Properties,Uses,Production

Uses

Selonsertib is an apoptosis signal-regulating kinase 1 (ASK1) inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. Selonsertib interacts with the catalytic kinase domain of ASK1 and prevents its phosphorylation and activation. As a result, the expression of genes involved in fibrosis, cellular proliferation, and apoptosis are down regulated.

Selonsertib Preparation Products And Raw materials

Raw materials

Preparation Products

Selonsertib Suppliers

Global( 130)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32835	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29899	58	Inquiry
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	China	2136	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49403	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Pharma Affiliates	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58

Selonsertib Spectrum

Selonsertib(1448428-04-3)¹HNMR

1448428-04-3(Selonsertib)Related Search:

GSK-114 GSK-626616 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Presatovir 4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE

S-Ruxolitinib (INCB018424) LOXO-292 Tofacitinib GDC-0084 SH-4-54

Osimertinib mesylate Tazemetostat (EPZ-6438) Niraparib Mertansine (S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate

Enasidenib Ivosidenib ABBV-075

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Selonsertib 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide GS 4997 Selonsertib GS-4997 GS-4497 GS-4997;ASK-1 GS4997 SELONSERTIB 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide Benzamide, 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]- CS-2217 GS4997;GS 4997 GS-4997; GS4997; GS 4997; SELONSERTIB FREE BASE. Selonsertib free base. Selonsertib (Synonyms: GS-4997) 1448428-04-3 C24H24FN7O API