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Rolapitant

Rolapitant Structure
CAS No.
552292-08-7
Chemical Name:
Rolapitant
Synonyms
Roltant;SCH619734;Rolapitant;Rolapitant-d4;Rolapitant HCl;brand name: Varubi;Rolapitant USP/EP/BP;SCH619734 SCH-619734;Rolapitant(sch619734);rolapitant,914462-92-3
CBNumber:
CB12628366
Molecular Formula:
C25H26F6N2O2
Molecular Weight:
500.48
MOL File:
552292-08-7.mol
Modify Date:
2024/7/2 8:55:00
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Rolapitant Properties

Boiling point 523.5±50.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 16 mg/ml; Ethanol: 3 mg/ml
pka 15.88±0.40(Predicted)
form Powder
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P281-P308+P313-P405-P501

Rolapitant Chemical Properties,Uses,Production

Definition

ChEBI: An azaspiro compound that is 1,7-diazaspiro[4.5]decan-2-one carrying additional phenyl and 1-{[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl substituents at position 8. Used (in the form of the hydrochloride hydrate) for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy.

Rolapitant Preparation Products And Raw materials

Raw materials

Preparation Products

Rolapitant Suppliers

Global( 124)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Hebei Duling International Trade Co. LTD +8617333973358 China 15437 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21675 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29900 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26114 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Supplier Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Pharma Affiliates 58
Hebei Duling International Trade Co. LTD 58
Henan Tianfu Chemical Co.,Ltd. 55
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
BOC Sciences 58
Chongqing Chemdad Co., Ltd 58
Dideu Industries Group Limited 58
AFINE CHEMICALS LIMITED 58

Rolapitant Spectrum

Rolapitant(552292-08-7)1HNMR

552292-08-7(Rolapitant)Related Search:

ROLIPRAM Rolapitant (1R,2S,3R)-Isomer Rolapitant (1S,2R,3R)-Isomer Rolapitant (1S,2R,3S)-Isomer Rolapitant (1R,2R,3S)-Isomer
ROLAPITANT HYDROCHLORIDE Rolapitant (1S,2S,3R)-Isomer Rolapitant (1S,2S,3S)-Isomer Rituximab Aprepitant
Emtricitabine Tacrolimus Sumatriptan Memantine
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Rolapitant (5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one hydrochloride. Rolapitant HCl Rolapitant(sch619734) (5S,8S)-8-[[[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl]oxy]methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one (5S,8S)-8-({(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one 1,7-Diazaspiro[4.5]decan-2-one,8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-,(5S,8S)- (5S,8S)-8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-1,9-diazaspiro[4.5]decan-2-one Rolapitant-d4 SCH619734 Rolapitant USP/EP/BP Roltant 3-Tritetradecanoylglycerol brand name: Varubi SCH619734 SCH-619734 rolapitant,914462-92-3 foot tapping,long-acting,emesis,retches,Rolapitant,NK receptor,Neurokinin Receptor,vomits,SCH 619734,SCH-619734,anti-emetic,Inhibitor,inhibit,orally active,Mongolian Gerbils,Tachykinin receptor,ferret (5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one 552292-08-7 C25H26F6N2O2