ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Aromatics >2-(4-Chlorophenoxy)-2-methylpropionic acid

2-(4-Chlorophenoxy)-2-methylpropionic acid

2-(4-Chlorophenoxy)-2-methylpropionic acid Structure
CAS No.
882-09-7
Chemical Name:
2-(4-Chlorophenoxy)-2-methylpropionic acid
Synonyms
PCIB;PCPIB;4-CPIB;Regadrin;Clofibrin;Regulipid;Clofibric;Arteriohom;Prestwick_39;AKOS BB-7852
CBNumber:
CB1282957
Molecular Formula:
C10H11ClO3
Molecular Weight:
214.65
MOL File:
882-09-7.mol
MSDS File:
SDS
Modify Date:
2024/1/3 13:33:01

2-(4-Chlorophenoxy)-2-methylpropionic acid Properties

Melting point 120-122 °C(lit.)
Boiling point 308.11°C (rough estimate)
Density 1.2413 (rough estimate)
refractive index 1.5220 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Methanol
pka 3.18±0.10(Predicted)
form Crystals or Crystalline Powder
color Pale yellow to brownish
Merck 14,2378
BRN 1874067
CAS DataBase Reference 882-09-7(CAS DataBase Reference)
NIST Chemistry Reference Clofibric acid(882-09-7)
EPA Substance Registry System Propanoic acid, 2-(4-chlorophenoxy)-2-methyl- (882-09-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312+P330-P501
Hazard Codes  Xn,Xi
Risk Statements  22-20/21/22
Safety Statements  36-24/25
WGK Germany  3
RTECS  UE9455000
HazardClass  IRRITANT
HS Code  29189900
NFPA 704
0
1 0

2-(4-Chlorophenoxy)-2-methylpropionic acid price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 90323 Clofibric acid analytical standard 882-09-7 100MG ₹6354.28 2022-06-14 Buy
Sigma-Aldrich(India) 197777 2-(p-Chlorophenoxy)-2-methylpropionic acid 97% 882-09-7 50G ₹7826.48 2022-06-14 Buy
TCI Chemicals (India) C0940 2-(4-Chlorophenoxy)isobutyric Acid 882-09-7 25G ₹3700 2022-05-26 Buy
Product number Packaging Price Buy
90323 100MG ₹6354.28 Buy
197777 50G ₹7826.48 Buy
C0940 25G ₹3700 Buy

2-(4-Chlorophenoxy)-2-methylpropionic acid Chemical Properties,Uses,Production

Description

Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 μM in a transactivation assay) and the active metabolite of clofibrate . It is formed from clofibrate by tissue and serum esterases. Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats. It decreases glutamate oxaloacetate transaminase (GOT) levels and increases glutamate pyruvate transaminase (GPT) and lactate dehydrogenase (LDH) levels, markers of xenobiotic stress, in the plasma of carp (C. carpio) when administered in tank water at a concentration of 10 μg/L. Clofibric acid has been found in wastewater effluent.

Chemical Properties

Pale Yellow Solid

Uses

Antilipemic.

Definition

ChEBI: A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.

Biological Activity

PPAR agonist. Antihyperlipoproteinemic.

2-(4-Chlorophenoxy)-2-methylpropionic acid Preparation Products And Raw materials

Global( 332)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6211 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Reax Chemicals 08048372701Ext 416 Hyderabad, India 4223 58 Inquiry
Eskay Engichem Pvt Ltd +91 20 32660087 Maharashtra, India 15 58 Inquiry
Vyas Bio Life Sciences Pvt. Ltd -65546373 Hyderabad, India 1213 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
Oceanic Pharmachem Pvt. Ltd. 91-22-42128600 Maharashtra, India 2006 58 Inquiry
CLOFIBRIC ACID 4-Chorophenoxy-d-methylpropionicacid 4-CPIB Chlorobenzene oxygenisobutyrate Acetic acid, (p-chlorop Prestwick_39 2-(4-Chlorophe Acetic acid, (p-chlorophenoxy)dimethyl- Acide (p-chlorophenoxy)-2 methyl-2 propionique acide(p-chlorophenoxy)-2methyl-2propionique alpha-(4-Chlorophenoxy)-alpha-methylpropionic acid alpha-(4-Chlorophenoxy)isobutyric acid Chlorfibrinic acid Chlorofibrinic acid Chlorophibrinic acid chlorophibrinicacid Clofibrate free acid Clofibrin Clofibrinsaeure p-(2,4-Chlorophenoxy)isobutyric acid p-Chlorophenoxyisobutyricacid PCIB Clofibric aCld 2-(4-Chlorophenoxy)-2-methylpropionic acid≥ 99% (HPLC) CLOFIBRINIC ACID ASISCHEM A27485 2-(P-CHLOROPHENOXY)-2-METHYLPROPIONIC ACID 2-(4-CHLOROPHENOXY)ISOBUTYRIC ACID 2-(4-CHLOROPHENOXY)-2-METHYLPROPANOIC ACID 2-(4-CHLOROPHENOXY)-2-METHYLPROPIONIC ACID 4-CHLOROPHENOXY-ISO-BUTYRIC ACID RARECHEM AL BO 0794 TIMTEC-BB SBB008306 AKOS BB-7852 AKOS B013926 ALPHA-(P-CHLOROPHENOXY)ISOBUTYRIC ACID (Chlorophenoxy)isobutyric acid (p-chlorophenoxy)dimethyl-aceticaci (p-Chlorophenoxy)isobutyric acid 2-(p-chlorophenoxy)-2-methyl-propionicaci 2-(p-Chlorophenoxy)isobutyric acid PCPIB Propanoic acid, 2-(4-chlorophenoxy)-2-methyl- Propanoic acid, 2-methyl, 2-(4-chlorophenyloxy) Propionic acid, 2-(p-chlorophenoxy)-2-methyl- Regadrin Regulipid 2-(4-Chlorophenoxy)-2-methylpropionic acid~Clofibric acid 4-CHLOROPHENOXY-ISO-BUTYRCC ACID p-chlorophenoxyisobutyrate ClofibricAcid98% [p-Chlorophenoxy]-2-methylpropionic acid a-(p-Chlorophenoxy)isobutyric Acid Arteriohom 4-Chlorophenoxy Clofibric p-Chlorophenoxyisobutyric acid, PCIB 4-CHLOROPHENOXYISO-BUTYRICACID(CLOFIBRICACID)