2-(4-Chlorophenoxy)-2-methylpropionic acid
![2-(4-Chlorophenoxy)-2-methylpropionic acid Structure](CAS/GIF/882-09-7.gif)
- CAS No.
- 882-09-7
- Chemical Name:
- 2-(4-Chlorophenoxy)-2-methylpropionic acid
- Synonyms
- PCIB;PCPIB;4-CPIB;Regadrin;Clofibrin;Regulipid;Clofibric;Arteriohom;Prestwick_39;AKOS BB-7852
- CBNumber:
- CB1282957
- Molecular Formula:
- C10H11ClO3
- Molecular Weight:
- 214.65
- MOL File:
- 882-09-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/1/3 13:33:01
Melting point | 120-122 °C(lit.) |
---|---|
Boiling point | 308.11°C (rough estimate) |
Density | 1.2413 (rough estimate) |
refractive index | 1.5220 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Chloroform, Methanol |
pka | 3.18±0.10(Predicted) |
form | Crystals or Crystalline Powder |
color | Pale yellow to brownish |
Merck | 14,2378 |
BRN | 1874067 |
CAS DataBase Reference | 882-09-7(CAS DataBase Reference) |
NIST Chemistry Reference | Clofibric acid(882-09-7) |
EPA Substance Registry System | Propanoic acid, 2-(4-chlorophenoxy)-2-methyl- (882-09-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P264-P270-P301+P312+P330-P501 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 22-20/21/22 | |||||||||
Safety Statements | 36-24/25 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | UE9455000 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29189900 | |||||||||
NFPA 704 |
|
2-(4-Chlorophenoxy)-2-methylpropionic acid price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 90323 | Clofibric acid analytical standard | 882-09-7 | 100MG | ₹6354.28 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 197777 | 2-(p-Chlorophenoxy)-2-methylpropionic acid 97% | 882-09-7 | 50G | ₹7826.48 | 2022-06-14 | Buy |
TCI Chemicals (India) | C0940 | 2-(4-Chlorophenoxy)isobutyric Acid | 882-09-7 | 25G | ₹3700 | 2022-05-26 | Buy |
2-(4-Chlorophenoxy)-2-methylpropionic acid Chemical Properties,Uses,Production
Description
Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 μM in a transactivation assay) and the active metabolite of clofibrate . It is formed from clofibrate by tissue and serum esterases. Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats. It decreases glutamate oxaloacetate transaminase (GOT) levels and increases glutamate pyruvate transaminase (GPT) and lactate dehydrogenase (LDH) levels, markers of xenobiotic stress, in the plasma of carp (C. carpio) when administered in tank water at a concentration of 10 μg/L. Clofibric acid has been found in wastewater effluent.
Chemical Properties
Pale Yellow Solid
Uses
Antilipemic.
Definition
ChEBI: A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.
Biological Activity
PPAR agonist. Antihyperlipoproteinemic.
2-(4-Chlorophenoxy)-2-methylpropionic acid Preparation Products And Raw materials
Raw materials
1of2
chevron_rightPreparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Reax Chemicals | 08048372701Ext 416 | Hyderabad, India | 4223 | 58 | Inquiry |
Eskay Engichem Pvt Ltd | +91 20 32660087 | Maharashtra, India | 15 | 58 | Inquiry |
Vyas Bio Life Sciences Pvt. Ltd | -65546373 | Hyderabad, India | 1213 | 58 | Inquiry |
Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
Oceanic Pharmachem Pvt. Ltd. | 91-22-42128600 | Maharashtra, India | 2006 | 58 | Inquiry |
Supplier | Advantage |
---|---|
CHEMSWORTH | 30 |
OCEAN TRADING CORPORATION | 58 |
A.J Chemicals | 58 |
CLEARSYNTH LABS LTD. | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Reax Chemicals | 58 |
Eskay Engichem Pvt Ltd | 58 |
Vyas Bio Life Sciences Pvt. Ltd | 58 |
Clearsynth Labs | 58 |
Oceanic Pharmachem Pvt. Ltd. | 58 |