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Mazindol

Mazindol Structure
CAS No.
22232-71-9
Chemical Name:
Mazindol
Synonyms
an448;42-548;Teronac;Terenac;Sanorex;Mazanor;sah42548;sa42-548;MAZINDOL;dimagrir
CBNumber:
CB1306743
Molecular Formula:
C16H13ClN2O
Molecular Weight:
284.74
MOL File:
22232-71-9.mol
Modify Date:
2023/6/8 9:02:50

Mazindol Properties

Melting point 215-217°C
Boiling point 454.9±55.0 °C(Predicted)
Density 1.39
refractive index 1.6330 (estimate)
storage temp. Controlled Substance, -20°C Freezer
solubility DMSO: 10 mg/mL
form powder
pka pKa 8.6 (Uncertain)
color white
CAS DataBase Reference 22232-71-9(CAS DataBase Reference)
NIST Chemistry Reference Mazindol(22232-71-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H300-H311+H331-H311-H331
Precautionary statements  P261-P280-P302+P352+P312-P304+P340+P312-P403+P233-P264-P301+P310-P311
Hazard Codes  T
Risk Statements  23/24/25
Safety Statements  36/37/39-45
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  NI2975000
HazardClass  6.1(a)
PackingGroup  II
Toxicity LD50 oral in rabbit: 98mg/kg
NFPA 704
0
4 0

Mazindol Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Clinical trials as appetite depressant. Anorexic; CNS stimulant. Controlled substance (stimulant).

World Health Organization (WHO)

Mazindol, an anorectic agent, was introduced into medicine in 1970 as an aid to weight reduction. It is controlled under Schedule IV of the 1971 Convention on Psychotropic Substances. It remains available in many countries with highly evolved drug regulatory authorities. (Reference: (UNCPS4) United Nations Convention on Psychotropic Substances (IV), , , 1971)

Mazindol Preparation Products And Raw materials

Raw materials

Preparation Products

1-a)isoindol-5-ol,2,5-dihydro-5-(4-chlorophenyl)-3h-imidazo( 1-a)isoindol-5-ol,5-(4-chlorophenyl)-2,5-dihydro-3h-imidazo( 1-a)isoindol-5-ol,5-(p-chlorophenyl)-2,5-dihydro-3h-imidazo( sa42-548 sah42548 SaH-42548 Sanorex Terenac Teronac MAZINDOLE MAZINDOOL MAZINDOL 5-[4-CHLOROPHENYL]-2,5-DIHYDRO-3H-IMIDAZO[2,1-A]ISOINDOL-5-OL 5-(4-chlorophenyl)-2,3-dihydro-5-hydroxy-5h-imidazo[2,1-a]isoindole mazindol--dea schedule iv item MAZINDOL BLOCKS NEURONAL MONOA 3H-Imidazo[2,1-a]isoindol-5-ol, 5-(4-chlorophenyl)-2,5-dihydro- (9CI) 3H-Imidazo[2,1-a]isoindol-5-ol, 5-(p-chlorophenyl)-2,5-dihydro- (8CI) 5-(p-Chlorophenyl)-5-hydroxy-2,3-dihydro-5H-imidazo[2,1-a]isoindole 5-Hydroxy-5-p-chlorophenyl-2,3-dihydro-5H-imidazo[2,1-a]isoindole 5-(4-chlorophenyl)-2,3-dihydro-5-hydroxy-5h-imidazo[2,1-a]isoindole 5-(4-chlorophenyl)-2,5-dihydro-3h-imidazo[2,1-a]isoindol-5-ol 5-(4-Chlorophenyl)-2,3-dihydro-5-hydroxy-5H-imidazol 5-(4-Chlorophenyl)-2,5-dihydro-3H-Imidazo 42-548 5-(4-Chlorophenyl)-2,3-dihydro-5H-imidazo[2,1-a]isoindol-5-ol 5-(4-chlorophenyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-ol Mazindol CIV (350 mg) 1-a]isoindol-5-ol,5-(4-chlorophenyl)-2,5-dihydro-3h-imidazo[ 3H-Imidazo[2,1-a]isoindol-5-ol, 5-(4-chlorophenyl)-2,5-dihydro- 5-(p-chlorophenyl)-2,5-dihydro-3h-imidazo(2,1-a)isoindol-5-ol 5-(p-Chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol 5H-Imidazo(2,1-a)isoindol-5-ol, 5-(4-chlorophenyl)-2,3-dihydro- 5h-imidazo(2,1-a)isoindol-5-ol,5-(4-chlorophenyl)-2,3-dihydro 5-p-Chlorophenyl-2,3-dihydro-5H-imidazo(2,1-a)isoindol-5-ol an448 dimagrir Magrilon Mazanor Mazildene SA 42-548 5-(4-chlorophenyl)-2,3-dihydroimidazo[1,2-b]isoindol-5-ol Mazindol (1.0 mg/mL in Methanol) Mazindol USP/EP/BP Mazindol CIV (1375309) 22232-71-9 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals