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OXYCODONE HYDROCHLORIDE

OXYCODONE HYDROCHLORIDE Structure
CAS No.
124-90-3
Chemical Name:
OXYCODONE HYDROCHLORIDE
Synonyms
OxyContin;OXYCODONE HCL;Combunox;Roxicodone;Oxycod;eubine;oxikon;oxycon;oxykon;eucodal
CBNumber:
CB1468375
Molecular Formula:
C18H22ClNO4
Molecular Weight:
351.82
MOL File:
124-90-3.mol
Modify Date:
2023/6/8 9:02:57
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OXYCODONE HYDROCHLORIDE Properties

Melting point 261-2630C
alpha D20 -125° (c = 2.5)
Flash point 11℃
storage temp. 2-8°C
solubility Freely soluble in water, sparingly soluble in anhydrous ethanol, practically insoluble in toluene.
Water Solubility 142.9g/L(temperature not stated)
CAS DataBase Reference 124-90-3

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H336
Precautionary statements  P261-P264-P270-P271-P301+P312-P304+P340+P312
Hazard Codes  Xn,T,F
Risk Statements  22-39/23/24/25-23/24/25-11
Safety Statements  36/37-45-16-7
RIDADR  UN 1230 3/PG 2
WGK Germany  3
RTECS  QD2470000
HazardClass  6.1(a)
PackingGroup  II
HS Code  2939110000
Toxicity cat,LDLo,intravenous,2500ug/kg (2.5mg/kg),LUNGS, THORAX, OR RESPIRATION: OTHER CHANGESBEHAVIORAL: ANALGESIA,Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 194, Pg. 296, 1940.
NFPA 704
0
2 0

OXYCODONE HYDROCHLORIDE Chemical Properties,Uses,Production

Description

Oxycodone (hydrochloride) (Item No. 26513) is an analytical reference standard categorized as an opioid. Oxycodone is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.

Chemical Properties

White Solid

Uses

Controlled substance (opiate). Analgesic (narcotic)

Biological Activity

Potent and selective μ -opioid receptor agonist (K i values are 16 and >1000 nM for hMOR1 and hKOR1 respectively).

Clinical Use

Oxycodone is about equipotent with morphine, but because of the 3-OCH group, it has a much lower oral:parenteral dose ratio. Thus, oxycodone is used orally to treat severe to moderate pain. It is a drug as a single agent and when combined in strong analgesic mixtures. Oxycodone has a plasma half-life of approximately 4 hours and requires dosing every 4 to 6 hours.

OXYCODONE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Acetic acid Hydrogen Potassium sodium tartrate tetrahydrate Dibutylurea tert-Butyldimethylsilyl chloride
Palladium hydroxide (5alpha)-7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one OXYCODONE THEBAINE
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Preparation Products

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OXYCODONE HYDROCHLORIDE 14-hydroxydihydrocodeinonehydrochloride 4,5-alpha-epoxy-14-hydroxy-3-methoxy-17-methyl-morphinan-6-onhydrochloride 4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-morphinan-6-one,hydrochloride,(5-a dihydronehydrochloride dihydrooxycodeinonehydrochloride (5a)-4,5-Epoxy-14-hydroxy-3-methoxy-17-methyl-morphinan-6-one Hydrochloride Supeudol oxycodone hydrochloride solution OXYCODONEHYDROCHLORIDE,USP 4,5a-Epoxy-14-hydroxy-3-methoxy-N-methyl-6-oxomorphinan hydrochloride Codeinone, 7,8-dihydro-14-hydroxy-, hydrochloride (6CI, 7CI) Dihydro-14-hydroxycodeinone hydrochloride Morphinan-6-one, 4,5a-epoxy-14-hydroxy-3-methoxy-17-methyl-, hydrochloride (8CI) Morphinan-6-one, 4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, hydrochloride, (5a)- (9CI) Oxycod Oxygesic 25333-72-6 (Terephthalate) 4,5-Epoxy-14-hydroxy-3-methoxy-17-methyl-morphinan-6-one, hydrochloride, (5-alpha)- (9ci) Oxycodone Hydrochloride (CII) Oxycodon HCL(injection grade) (5α)-4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-onehydrochloride Oxycodone Hydrochloride (CII), USP Oxycodone Hydrochloride CII (1 g) Morphinan-6-one,4,5-epoxy-14-hydroxy-3-Methoxy-17-Methyl-, hydrochloride (1:1), (5a)- dihydroxycodeinonehydrochloride dinarkon eubine eucodal eukodal eutagen oxikon oxycodonhydrochloride oxycon oxykodal oxykon pancodine percodanhydrochloride stupenone tecodin tecodine tekodin thecodin thecodine thekodin oxycodone hydrochloride--dea schedule*ii item OXYCODONE HYDROCHLORIDE*METHANOL SOLUTIO N OXYCODONE HYDROCHLORIDE NARCOTIC ANALGES IC MUZQPDBAOYKNLO-RKXJKUSZSA-N Oxycodone Hydrochloride (1.0mg/ml in Methanol) Oxycodone Hydrochloride CII (1485205) OXYCODONE HCL Roxicodone OxyContin Combunox Hydrocodone Hydrogen Tartrate 2.5-Hydrate EP Impurity D as Hydrochloride 124-90-3 C18H22ClNO4