fenclofenac

fenclofenac Structure
CAS No.
34645-84-6
Chemical Name:
fenclofenac
Synonyms
Flenac;R 67408;RX 67408;fenclofenac;[o-(2,4-Dichlorophenoxy)phenyl]acetic acid;Benzeneacetic acid, 2-(2,4-dichlorophenoxy)-;2-[2-(2,4-dichlorophenoxy)phenyl]acetic acid
CBNumber:
CB1885619
Molecular Formula:
C14H10Cl2O3
Molecular Weight:
297.136
MOL File:
34645-84-6.mol
Modify Date:
2023/5/4 17:34:38

fenclofenac Properties

Melting point 135.0℃
Boiling point 410.72°C (rough estimate)
Density 1.3076 (rough estimate)
refractive index 1.5209 (estimate)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka pKa 4.53 (Uncertain)
color Off-White to Light Brown
Water Solubility 8.439mg/L(25 ºC)
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Toxicity LD50 oral in rat: 2280mg/kg

fenclofenac Chemical Properties,Uses,Production

Uses

Anti-inflammatory.

World Health Organization (WHO)

Fenclofenac, a nonsteroidal anti-inflammatory agent, was introduced in 1978 for the treatment of rheumatic disorders. By 1984 its use in the United Kingdom was associated with serious adverse effects, predominantly skin rashes, some of which were fatal. This led to the UK Committee on Safety of Medicine's refusal to renew the product licence and to the subsequent withdrawal of the drug by the manufacturer in all countries in which it was marketed.

fenclofenac Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 17)Suppliers
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Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
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Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
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Shanghai Worldyang Chemical Co.,Ltd. 021-021-56795766 China 9352 58 Inquiry
W & J PharmaChem, Inc. +1 (301) 880-0624 United States 595 50 Inquiry
fenclofenac [o-(2,4-Dichlorophenoxy)phenyl]acetic acid Flenac R 67408 RX 67408 2-[2-(2,4-dichlorophenoxy)phenyl]acetic acid Benzeneacetic acid, 2-(2,4-dichlorophenoxy)- 34645-84-6