2,4-Dichlorophenol
- CAS No.
- 120-83-2
- Chemical Name:
- 2,4-Dichlorophenol
- Synonyms
- 2,4-DCP;Isobac;a13-00078;NCI-C55345;2,4-Phenol;2,4-Dichlorphenol;2,4-dichloro-pheno;2,4-dlchlorophenol;2,4-DICHLOROPHENOL;4,6-dichlorophenol
- CBNumber:
- CB4458696
- Molecular Formula:
- C6H4Cl2O
- Molecular Weight:
- 163
- MOL File:
- 120-83-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/14 15:18:26
| Melting point | 42-43 °C(lit.) |
|---|---|
| Boiling point | 209-210 °C(lit.) |
| Density | 1.383 |
| vapor pressure | 1.3 hPa (50 °C) |
| refractive index | 1.4430 (estimate) |
| Flash point | 237 °F |
| storage temp. | 2-8°C |
| solubility | methanol: soluble1g in 10ml |
| pka | pK1:7.85 (25°C) |
| color | White to beige |
| Water Solubility | 4.5 g/L (20 ºC) |
| Merck | 14,3072 |
| BRN | 742467 |
| Henry's Law Constant | 2.88 x 10-6 atm?m3/mol at 20 °C (Sheikheldin et al., 2001) 3.23 x 10-6 atm?m3/mol at 25 °C (estimated, Leuenberger et al., 1985a) |
| InChIKey | HFZWRUODUSTPEG-UHFFFAOYSA-N |
| LogP | 3.25 at 20℃ |
| CAS DataBase Reference | 120-83-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Phenol, 2,4-dichloro-(120-83-2) |
| EPA Substance Registry System | 2,4-Dichlorophenol (120-83-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS06,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H311-H314-H411 | |||||||||
| Precautionary statements | P260-P273-P280-P301+P312-P303+P361+P353-P305+P351+P338 | |||||||||
| Hazard Codes | T,N,F | |||||||||
| Risk Statements | 22-24-34-51/53-39/23/24/25-23/24/25-11-25 | |||||||||
| Safety Statements | 26-36/37/39-45-61-36/37-16-7 | |||||||||
| RIDADR | UN 2928 6.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | SK8575000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29081000 | |||||||||
| Toxicity | Acute oral LD50 for mice 1,276 mg/kg, rats 580 mg/kg (quoted, RTECS, 1985). | |||||||||
| NFPA 704 |
|
2,4-Dichlorophenol price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 8.03774 | 2,4-Dichlorophenol for synthesis | 120-83-2 | 100G | ₹3590 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR2595 | 2,4-dichlorophenol Pharmaceutical Secondary Standard; Certified Reference Material | 120-83-2 | 200MG | ₹17038.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.03774 | 2,4-Dichlorophenol for synthesis | 120-83-2 | 500G | ₹5620.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 105953 | 2,4-Dichlorophenol 99% | 120-83-2 | 5G | ₹1656.23 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 105953 | 2,4-Dichlorophenol 99% | 120-83-2 | 100G | ₹2067.58 | 2022-06-14 | Buy |
2,4-Dichlorophenol Chemical Properties,Uses,Production
Chemical Properties
white to beige crystalline solid
Physical properties
Colorless to yellow crystals with a sweet, musty, or medicinal odor. At 40 °C, the average odor threshold concentration and the lowest concentration at which an odor was detected were 29 and 5.4 μg/L, respectively. Similarly, at 25 °C, the average taste threshold concentration and the lowest concentration at which a taste was detected were 2.5 and 0.98 μg/L, respectively (Young et al., 1996).
Uses
2,4-Dichlorophenol is a chlorinated derivative of phenol and is used as an intermediate for the preparation of herbicide 2,4-dichlorophenoxyacetic acid (D435680).
Definition
ChEBI: A dichlorophenol that is phenol carrying chloro substituents at positions 2 and 4.
General Description
Colorless crystalline solid with a medicinal odor. Melting point 45°C. Sinks in water. Strong irritant to tissues; toxic by ingestion.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2,4-Dichlorophenol can react vigorously with oxidizing agents. Can also react with acids or acid fumes. Incompatible with acid chlorides and acid anhydrides.
Health Hazard
Tremors, convulsions, shortness of breath, inhibition of respiratory system.
Safety Profile
Suspected carcinogen with experimental carcinogenic and teratogenic data. Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Mutation data reported. Combustible when exposed to heat or flame. Can react vigorously with oxidizing materials. To fight fre, use alcohol foam, foam, CO2, dry chemical. When heated to decomposition, or on contact with acid or acid fumes, it emits hghly toxic fumes of Cl-. See also CHLOROPHENOLS.
Potential Exposure
2,4-Dichlorophenol is a commercially produced substituted phenol used in the manufacture of industrial and agricultural products; in synthesis of pharmaceuticals. As an intermediate in the chemical industry, 2,4-DCP is utilized as the feedstock for the manufacture of 2,4-dichlorophenoxyacetic acid (2,4-D), and 2,4-D derivatives (germicides, soil sterilants, etc.); certain methyl compounds used in mothproofing, antiseptics and seed disinfectants. 2,4-DCP is also reacted with benzene sulfonyl chloride to produce miticides or further chlorinated to pentachlorophenol, a wood preservative. It is thus a widely used pesticide intermediate. The only group expected to be at risk for high exposure to 2,4-DCP is industrial workers involved in the manufacturing or handling of 2,4-DCP and 2,4-D
Carcinogenicity
In mammalian cells in vitro 2,4-DCP produced
chromosomal aberrations and induced
unscheduled DNA synthesis; it was negative
for sister chromatid exchange in vivo and was
mostly negative in bacterial assays.
Oral exposure of pregnant rats to
750mg/kg/day for 10 gestational days induced
slightly decreased fetal weight, delayed ossification
of sternal and vertebral arches, and some
early embryonic deaths.10 Maternal deaths also
occurred at this dose, indicating that 2,4-DCP
was not selectively toxic to embryos or fetuses.
No effects were noted in dams or offspring
exposed at 375mg/kg/day.
A threshold limit value (TLV) has not been
established for 2,4-dichlorophenol.
Shipping
UN2020 Chlorophenols, solid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials
Purification Methods
Crystallise it from pet ether (b 30-40o). Purify it also by repeated zone melting, using a P2O5 guard tube to exclude moisture. It is very hygroscopic when dry. [Beilstein 6 IV 885.]
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Contact with acids or acid fumes causes decomposition releasing poisonous chlorine gas. Incompatible with caustics, acid anhydrides; acid chlorides. Quickly corrodes aluminum; slowly corrodes zinc, tin, brass, bronze, copper and its alloys. May accumulate static electrical charges, and may cause ignition of its vapors.
Waste Disposal
Dissolve in a combustible solvent and incinerate in a furnace equipped with afterburner and scrubber. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≧100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal
2,4-Dichlorophenol Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
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|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| Reenold Enterprises | +91-8208173540 +91-8208173540 | Maharashtra, India | 28 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| CNS CHEMICALS | +91-9381957258 +91-9381957258 | Telangana, India | 354 | 58 | Inquiry |
| Aarti Industries Limited (AIL) | +91-84596144931 +91-9920899935 | Maharashtra, India | 235 | 58 | Inquiry |
| Super Hygienic Chemicals | +91-9821095252 +91-9821095252 | Mumbai, India | 23 | 58 | Inquiry |
| Benzo Chem Industries Pvt. Ltd. | 91-22-43555888 | Maharashtra, India | 71 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Scientific OEM | +91-22- 2343 7546 / 2341 3094 | New Delhi, India | 1996 | 38 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| Reenold Enterprises | 58 |
| JSK Chemicals | 58 |
| CNS CHEMICALS | 58 |
| Aarti Industries Limited (AIL) | 58 |
| Super Hygienic Chemicals | 58 |
| Benzo Chem Industries Pvt. Ltd. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Scientific OEM | 38 |
| OCEAN TRADING CORPORATION | 58 |