2,4,6-Trichlorophenol
- CAS No.
- 88-06-2
- Chemical Name:
- 2,4,6-Trichlorophenol
- Synonyms
- 2,4,6-TCP;Phenol, 2,4,6-trichloro-;2,4,6-TrichL;2,4,6-Trichlorophenol (2,4,6-Tcp);OMAL;2,4,6 T;ai3-00142;dowcide2s;phenaclor;BTS 45186
- CBNumber:
- CB3854536
- Molecular Formula:
- C6H3Cl3O
- Molecular Weight:
- 197.45
- MOL File:
- 88-06-2.mol
- Modify Date:
- 2024/8/15 16:24:08
| Melting point | 64-66 °C(lit.) |
|---|---|
| Boiling point | 246 °C(lit.) |
| Density | 1.49 |
| vapor pressure | 1 mm Hg ( 76.5 °C) |
| refractive index | 1.5300 (estimate) |
| Flash point | 99 °C |
| storage temp. | Store below +30°C. |
| solubility | 0.8g/l |
| form | Crystalline Mass or Crystalline Powder and Chunks |
| pka |
6.15 (Leuenberger et al., 1985) 6.10 (Blackman et al., 1955) 6.0 (Eder and Weber, 1980) |
| color | white to slightly brown |
| Water Solubility | 0.8 g/L |
| Merck | 14,9644 |
| BRN | 776729 |
| Henry's Law Constant | 9.07 at 25 °C (estimated, Leuenberger et al., 1985a) |
| CAS DataBase Reference | 88-06-2(CAS DataBase Reference) |
| IARC | 2B (Vol. 117) 2019 |
| NIST Chemistry Reference | Phenol, 2,4,6-trichloro-(88-06-2) |
| EPA Substance Registry System | 2,4,6-Trichlorophenol (88-06-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS07,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H351-H410 | |||||||||
| Precautionary statements | P201-P273-P301+P312-P302+P352-P305+P351+P338-P308+P313 | |||||||||
| Hazard Codes | Xn,N,T,F | |||||||||
| Risk Statements | 22-36/38-50/53-40-52/53-39/23/24/25-23/24/25-11-51/53 | |||||||||
| Safety Statements | 36/37-60-61-45-16 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | SN1575000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29081000 | |||||||||
| Toxicity | LD50 orally in Rabbit: 887 mg/kg | |||||||||
| NFPA 704 |
|
2,4,6-Trichlorophenol price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T55301 | 2,4,6-Trichlorophenol 98% | 88-06-2 | 50G | ₹4297.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T55301 | 2,4,6-Trichlorophenol 98% | 88-06-2 | 250G | ₹6072.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T55301 | 2,4,6-Trichlorophenol 98% | 88-06-2 | 1KG | ₹19744.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.18469 | 2,4,6-Trichlorophenol for synthesis | 88-06-2 | 100G | ₹3760 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.18469 | 2,4,6-Trichlorophenol for synthesis | 88-06-2 | 1KG | ₹17550 | 2022-06-14 | Buy |
2,4,6-Trichlorophenol Chemical Properties,Uses,Production
Chemical Properties
Yellow flakes; strong phenolic odor. Soluble in acetone, alcohol, and ether; insoluble in water. Nonflammable.
Physical properties
Colorless needles or yellow solid with a strong, phenolic, musty or rotten vegetable-type odor. At 40 °C, the lowest concentration at which an odor was detected was 380 μg/L. At 25 °C, the lowest concentration at which a taste was detected was >12 μg/L (Young et al., 1996).
Uses
2,4,6-Trichlorophenol is used as a broad range pesticide against insects, fungi, vegetation and bacteria. It has become a common environmental contaminant and probable human carcinogen.
Definition
ChEBI: A trichlorophenol with phenolic substituents on positions 2, 4 and 6.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2,4,6-Trichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents. 2,4,6-Trichlorophenol can be converted to the sodium salt by reaction with sodium carbonate. Forms ethers, esters and salts by reaction with metals and amines. Undergoes substitution reactions such as nitration, alkylation, acetylation and halogenation. Can be hydrolyzed by reaction with bases at elevated temperatures and pressures. Reacts with alkalis at high temperatures .
Health Hazard
In experimental animals, 2,4,6- trichlorophenol causes toxic effects to the liver and hematologic system and cancer. There is no reliable information regarding exposure and toxic effects in humans.
Fire Hazard
Literature sources indicate that 2,4,6-Trichlorophenol is nonflammable.
Safety Profile
Confirmed carcinogen with experimental carcinogenic data. Poison by intraperitoneal route. Moderately toxic by ingestion and skin contact. A skin and severe eye irritant. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl-. Used as a germicide and preservative. See also CHLOROPHENOLS.
Carcinogenicity
2,4,6-Trichlorophenol is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Environmental Fate
Biological. In activated sludge, only 0.3% mineralized to carbon dioxide after 5 d (Freitag et al.,
1985). In anaerobic sludge, 2,4,6-trichlorophenol degraded to 4-chlorophenol (Mikesell and Boyd,
1985). When 2,4,6-trichlorophenol was statically incubated in the dark at 25 °C with yeast extract
and settled domestic wastewater inoculum, significant biodegradation with rapid adaptation was
observed. At concentrations of 5 and 10 mg/L, 96 and 97% biodegradation, respectively, were
observed after 7 d (Tabak et al., 1981).
Photolytic. Titanium dioxide suspended in an aqueous solution and irradiated with UV light (λ
= 365 nm) converted 2,4,6-trinitrophenol to carbon dioxide at a significant rate (Matthews, 1986).
A carbon dioxide yield of 65.8% was achieved when 2,4,6-trichlorophenol adsorbed on silica gel
was irradiated with light (λ >290 nm) for 17 h (Freitag et al., 1985).
Chemical/Physical. An aqueous solution containing chloramine reacted with 2,4,6-trichlorophenol
to yield the following intermediate products after 2 h at 25 °C: 2,6-dichloro-1,4-
benzoquinone-4-(N-chloro)imine and 4,6-dichloro-1,2-benzoquinone-2-(N-chloro)imine (Maeda et
al., 1987).
Purification Methods
Crystallise the phenol from *benzene, EtOH or EtOH/water. [Beilstein 6 IV 1005.]
2,4,6-Trichlorophenol Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Aarti Industries Limited (AIL) | +91-84596144931 +91-9920899935 | Maharashtra, India | 235 | 58 | Inquiry |
| Super Hygienic Chemicals | +91-9821095252 +91-9821095252 | Mumbai, India | 23 | 58 | Inquiry |
| CNS CHEMICALS | +91-9381957258 +91-9381957258 | Telangana, India | 354 | 58 | Inquiry |
| Valiant Organics Limited | 91-22-67976683 | Maharashtra, India | 2 | 58 | Inquiry |
| S. N. Chemicals | 91-9309242010 | Rajasthan, India | 16 | 58 | Inquiry |
| Cns Chemicals | 08066085913Ext 735 | Hyderabad, India | 262 | 58 | Inquiry |
| Perfect Chemical | 08048372764Ext 379 | Mumbai, India | 171 | 58 | Inquiry |
| Titan Biotech Limited | 09711169006 | Delhi, India | 196 | 58 | Inquiry |
| Chemico | 09166312452 | Mumbai, India | 235 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Aarti Industries Limited (AIL) | 58 |
| Super Hygienic Chemicals | 58 |
| CNS CHEMICALS | 58 |
| Valiant Organics Limited | 58 |
| S. N. Chemicals | 58 |
| Cns Chemicals | 58 |
| Perfect Chemical | 58 |
| Titan Biotech Limited | 58 |
| Chemico | 58 |
| OCEAN TRADING CORPORATION | 58 |