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LAVENDUSTIN A

CAS No.: 125697-92-9

Chemical Name:: LAVENDUSTIN A

Synonyms: RG14355;NSC 678027;LAVENDUSTIN A;Lavendustin A,98%;RG-14355;NSC 678027;LAVENDUSTIN A USP/EP/BP;Lavendustin A - CAS 125697-92-9 - Calbiochem;5-AMINO-[(N-2,5-DIHYDROXYBENZYL)-N'-2-HYDROXYBENZYL]SALICYLIC ACID;5-[(2,5-Dihydroxybenzyl)(2-hydroxybenzyl)amino]-2-hydroxybenzoic acid;5-[[(2,5-DIHYDROXYPHENYL)METHYL][(2-HYDROXYPHENYL)METHYL]AMINO]-2-HYDROXYBENZOIC ACID

CBNumber:: CB2135704

Molecular Formula:: C21H19NO6

Molecular Weight:: 381.38

MOL File:: 125697-92-9.mol

Modify Date:: 2023/5/18 11:31:16

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LAVENDUSTIN A Properties

Melting point	205-215 °C
Boiling point	741.7±60.0 °C(Predicted)
Density	1.495±0.06 g/cm3(Predicted)
RTECS	DG8578950
storage temp.	−20°C
solubility	DMSO: soluble
pka	2.31±0.10(Predicted)
form	crystalline
color	Yellow to brown
Sensitive	Air Sensitive
Stability	Moisture Sensitive: Hygroscopic
CAS DataBase Reference	125697-92-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	37/39-26
WGK Germany	3
HS Code	29225000

LAVENDUSTIN A price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	428150	Lavendustin A - CAS 125697-92-9 - Calbiochem A cell-permeable, reversible, and substrate competitive inhibitor of EGF receptor tyrosine kinase and p60c-src with little effect on protein kinase A	125697-92-9	1MG	₹19050	2022-06-14	Buy

Product number	Packaging	Price	Buy
428150	1MG	₹19050	Buy

LAVENDUSTIN A Chemical Properties,Uses,Production

Description

Lavendustin A is a selective inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase (IC₅₀ = 11 nM) that was first isolated from a Streptomyces culture filtrate. It does not inhibit protein kinase A (PKA), PKC, or PI3K (IC₅₀s > 100 μM). It has been used to differentiate rat mesenchymal stem cells, to inhibit NMDA-stimulated cGMP production, and to inhibit VEGF-induced angiogenesis.

Chemical Properties

Off-White Solid

Biological Activity

Potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC 50 = 11 nM). Inhibits p60 c-src with an IC 50 of 500 nM and is selective over PKA, PKC and PI 3-kinase (IC 50 > 100 μ M).

LAVENDUSTIN A Preparation Products And Raw materials

Raw materials

Preparation Products

LAVENDUSTIN A Suppliers

Global( 83)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	China	5738	58	Inquiry
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd	+86-86-22-87899925 +86-8618522618860	China	694	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	25655	58	Inquiry
Alfa Chemistry		United States	24072	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354	United States	19973	58	Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	China	11681	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd	58
Dideu Industries Group Limited	58
Alfa Chemistry	58
InvivoChem	58
TargetMol Chemicals Inc.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Amadis Chemical Company Limited	58

125697-92-9(LAVENDUSTIN A)Related Search:

METHYL 2,5-DIHYDROXYCINNAMATE H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH AG 825 TYRPHOSTIN A25 Canertinib

Lavendustin C Analog, Methyl-4-[N-(2μ,5μ-dihydroxybenzyl)amino]benzoate,LAVENDUSTIN C ANALOG N,N-DIBENZYLANILINE 3-(Dimethylamino)benzoic acid Ethylbenzyltoluidine LAVENDUSTIN A

5-Dimethylamino-2-hydroxybenzaldehyde LAVENDUSTIN C 2-(BENZYLAMINO-METHYL)-PHENOLHYDROCHLORIDE 3-(DIETHYLAMINO)BENZOIC ACID LAVENDUSTIN B

lavendustin C6 LAVENDUSTIN C METHYL ESTER LAVENDUSTIN A METHYL ESTER

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RG14355 LAVENDUSTIN A 5-AMINO-[(N-2,5-DIHYDROXYBENZYL)-N'-2-HYDROXYBENZYL]SALICYLIC ACID 5-[[(2,5-DIHYDROXYPHENYL)METHYL][(2-HYDROXYPHENYL)METHYL]AMINO]-2-HYDROXYBENZOIC ACID 5-[(2,5-Dihydroxybenzyl)(2-hydroxybenzyl)amino]-2-hydroxybenzoic acid Lavendustin A,98% NSC 678027 Benzoic acid,5-[[(2,5-dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino]-2-hydroxy- Lavendustin A - CAS 125697-92-9 - Calbiochem RG-14355;NSC 678027 LAVENDUSTIN A USP/EP/BP 125697-92-9 BioChemical Cell Biology Cell Signaling and Neuroscience Kinase/Phosphatase Biology Receptor Tyrosine Kinase Inhibitors Tyrosine Kinase (TK) Miscellaneous Natural Products All Inhibitors Inhibitors Tyrosine Kinase Inhibitors