LAVENDUSTIN C

LAVENDUSTIN C Structure
CAS No.
125697-93-0
Chemical Name:
LAVENDUSTIN C
Synonyms
HDBA;NSC 666251;COMPOUND 5;LAVENDUSTIN C;Lavendustin C (HDBA);5-(2,5-DIHYDROXYBENZYLAMINO)SALICYLIC ACID;5-(N-2,5-DIHYDROXYBENZYL)AMINOSALICYLIC ACID;5-(N-2',5'-DIHYDROXYBENZYL)AMINOSALICYLIC ACID;N-(2',5'-DIHYDROXYBENZYL)-5-AMINOSALICYLIC ACID;2-hydroxy-5-(2,5-dihydrobenzyl)aminobenzoic acid
CBNumber:
CB5135705
Molecular Formula:
C14H13NO5
Molecular Weight:
275.26
MOL File:
125697-93-0.mol
MSDS File:
SDS
Modify Date:
2023/9/20 16:43:00

LAVENDUSTIN C Properties

Melting point 193-195°C dec.
Boiling point 597.5±50.0 °C(Predicted)
Density 1.551±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO: soluble
form solid
pka 2.32±0.10(Predicted)
color Light Beige to Brown
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H335-H319-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
3-10
NFPA 704
0
2 0

LAVENDUSTIN C Chemical Properties,Uses,Production

Description

Lavendustin C, a derivative of a Streptomyces griseolavendus butyl acetate extract, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 value of 0.012 μM. Lavendustin C also inhibits pp60c-src(+) kinase and Ca2+ calmodulin-dependent kinase II with IC50 values of 0.5 and 0.2 μM, respectively. At a concentration of 10-150 μM, lavendustin C inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation.

Chemical Properties

Brown Solid

LAVENDUSTIN C Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 87)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32836 60 Inquiry
Jinan Carbotang Biotech Co.,Ltd. +8615866703830 China 7621 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Hebei Guanlang Biotechnology Co., Ltd. +8619930503259 China 18423 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Shaanxi Xihua Chemical Industry Co., Ltd 17691182729 15529505138 China 9962 58 Inquiry
Krain Pharmaceutical Technology CO.,Ltd 18252089365 China 2618 58 Inquiry
BOC Sciences USA 0 65 Inquiry

LAVENDUSTIN C Spectrum

2-hydroxy-5-(2,5-dihydrobenzyl)aminobenzoic acid Compound 5, HDBA, N-(2μ,5μ-Dihydroxybenzyl)-5-aminosalicylic acid, [2-Hydroxy-5-[N-(2μ,5μ-dihydroxybenzyl)amino]benzoic acid 5-(2,5-Dihydroxybenzylamino)salicylic acid, N-(2,5-Dihydroxybenzyl)-5-aminosalicylic acid 5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoic acid 5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxy-benzoic acid NSC 666251 2-HYDROXY-5-(2,5-DIHYDROXYBENZYLAMINO)BENZOIC ACID [2-HYDROXY-5-[N-(2',5'-DIHYDROXYBENZYL)AMINO]BENZOIC ACID 5-(2,5-DIHYDROXYBENZYLAMINO)-2-HYDROXYBENZOIC ACID 5-(2,5-DIHYDROXYBENZYLAMINO)SALICYLIC ACID 5-(N-2',5'-DIHYDROXYBENZYL)AMINOSALICYLIC ACID 5-(N-2,5-DIHYDROXYBENZYL)AMINOSALICYLIC ACID HDBA COMPOUND 5 LAVENDUSTIN C N-(2',5'-DIHYDROXYBENZYL)-5-AMINOSALICYLIC ACID Benzoic acid, 5-[[(2,5-dihydroxyphenyl)methyl]amino]-2-hydroxy- Lavendustin C (HDBA) N-(2-((2-((4Z,7Z,10Z,13Z,16Z,19Z)-DOCOSA-4,7,10,13,16,19-HEXAENAMIDO)ETHYL)DISULFANYL)-2-METHYLPROPYL)NICOTINAMIDE HER1,ErbB-1,EGFR,inhibit,Inhibitor,Calmodulin-dependent protein kinases,calmodulin-dependent,Src,lavendustin C,pp60,CaMK,Ca2+,Epidermal growth factor receptor,tyrosine,kinase,Calmodulin-dependent kinases 125697-93-0 Chelators Cell Signaling and Neuroscience Receptor Tyrosine Kinase Inhibitors Tyrosine Kinase (TK) Kinase/Phosphatase Biology Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Type Enzyme Inhibitors Cell Biology BioChemical Biochemicals and Reagents Other enzyme inhibitors and activators All Inhibitors Inhibitors Tyrosine Kinase Inhibitors